Glucocorticoids

Question 1

glucocorticoid meds

Answer 1

oral:
prednisone
prednisolone
methylprednisolone

IV:
dexamethasone

Question 2

mechanism of action for glucocorticoids

Answer 2

increase cortisol levels to supress inflammatory immune response

Question 3

adverse effects of glucocorticoids

Answer 3

C ataract
U lcer
S kin thinning
H ypertension, hypokalemia
I nsomnia
N eck and fat fat (obesity)
G lucose levels elevated
O steoporosis
I nfection
D epression

Question 4

adrenal insufficiency

Answer 4

associated w/abrupt glucocorticoid discontinuation; endogenous cortisol discontinued d/t previous exogenous cortisol levels, leaving body w/o innate cortisol and a vulnerable immune system

sx: flu-like, hypotension