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NUR 408 Pharmacotherapeutics > Acetaminophen > Flashcards

Acetaminophen Flashcards

1
Q

acetaminophen mechanism of action

A

CNS ONLY enzyme inhibition to decrease pain and fever

broken down by liver into toxic compound which must be combated with glutathione

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2
Q

liver toxicity w/acetaminophen

A 
3-4g maximum daily
high risk:
malnourished (no glutathione)
ETOH (CYP inducer-->increase absorption/toxic compound)
liver dz
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3
Q

antidote for acetaminophen OD

A

acetylcysteine
replaces glutathione
effective w/in 8-10 hr

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NUR 408 Pharmacotherapeutics (22 decks)

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