Antispasmodics Flashcards
1
Q
common uses for antispasmodics
A
muscles spasms d/t injury
spasticity d/t cerebral palsy, spinal cord injury, MS
malignant hyperthermia (anesthesia rxn)
2
Q
antispasmodics to know
A
diazepam
cyclobenzaprine
baclofen
dantrolene
3
Q
antispasmodic mechanism of action
A
enhance GABA to sedate CNS (except dantrolene)
4
Q
dantrolene mechanism of action
A
suppresses release of calcium w/in muscle, which weakens muscle and makes it difficult to contract
5
Q
issues w/antispasmodic meds
A
CNS depression
avoid:
heavy machinery
ETOH
6
Q
issues w/baclofen
A
abrupt discontinuation may causes hallucinations, seizures, paranoid ideations
7
Q
issues w/dantrolene
A
hepatoxicity 1 in 1000
check liver function prior to tx and monitor
