NeuroHistology Flashcards

1
Q

Neurons are mitotic or amitotic?

And what does it mean

A

Amitotic

do not undergo mitosis

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2
Q

Neurons

-communicate with each other at synapses of neuron to neuron or of neuron to effector junction like____ or____

A

NMJ

NGJ

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3
Q

Do NEURONES have high or low rate of aerobic respiration

and is this and advantage or a disadvantage

And why?

A

High rate

Disadvantage

because if breathing is lost for about 3 mins, there is cessation of respiration

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4
Q

contacts possible for dendrites are : dendro_____ ;dendro_____; dendro_____

A

dendritic

somatic

axonal

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5
Q

in CNS, tumors arise from ______of_____ cells

A

abnormal division

glial

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6
Q

Neuroglial cells

Mitotic or amitotic

A

Mitotic throughout life

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7
Q

ASTROCYTES
-connect neurons to____

Has 2 types: list them

A

blood supply

Fibrous and protoplasmic

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8
Q

Who has thicker dendrites?

Fibrous or protoplasmic Astrocyte?

A

Protoplasmic

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9
Q

EPENDYMAL CELLS

  • ___layer of_____ epithelium with____ lining the brain ventricles and central canal of spinal cord
  • produce——-
A

single; cuboidal

microvilli

CSF

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10
Q

when there is injury to brain tissue, there is rapid proliferation of_____ neuroglial cells and this can be used for diagnosis

A

Astrocytes

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11
Q

Multiple sclerosis

  • is the———- leading to formation of ———in CNS
  • causes ——- eventually
A

destruction of myelin sheath;plaque

paralysis

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12
Q

Multiple sclerosis

diminishes or enhances impulse conduction

A

Diminishes

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13
Q

Is Multiple sclerosis sex linked recessive?

A

No.. sex linked dominant

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14
Q

Multiple sclerosis found in____ gender while_____ gender are carriers

A

men

women

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15
Q

Multiple sclerosis doesn’t even express itself in males till about—- years

A

30

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16
Q

Examples of a famous person that suffered from MS

A

Anthony Hawkins, a British physicist, suffered from MS

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17
Q

Swiss roll theory

  • used to explain how ———-
  • also calls it the ———-theory
A

myelin sheath wraps around the nerve fiber

jelly-roll

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18
Q

myelin increases speed of impulse conduction and the energy required for conduction
T/F

A

F

myelin increases speed of impulse conduction and reduces the energy required for conduction

19
Q

Schwann cell produce a——— appearance

A

laminar

20
Q
CLASSICFICATION of neurons based on AXONS
———
———
———-
————
A

True Unipolar
Pseudounipolar
Bipolar
Multipolar

21
Q

True Unipolar neurons

  • ____axons or______ ones
  • present in____ brain
A

no

super short

fetal

22
Q

Pseudounipolar

-found in______ of nerves

A

dorsal root ganglion

23
Q

Bipolar neurons

  • found in_____
  • eg______ of the retina
  • cells of the———- of the ear
  • _____nerve cells of the tongue
  • _____cells of the nose
A

special organ senses

rod and cone cells

organ of corti

taste bud

olfactory mucosa

24
Q

Multipolar neurons

  • found from____ to———
  • eg_____ cells of cerebrum;—— cells of cerebellum(located in the____ parts of the cerebellar cortex and can be seen with____ staining)
A

Brian; spinal cord

pyramidal; purkinje

lowest

silver

25
Q

Most neurons in the CNS are of what type ????

A

Multipolar

26
Q

Coverings sha

  • each axon is covered by an ——neurium
  • each fascicle is covered by ——neurium
  • general nerve bundle is covered by ——neurium
A

endo

peri

epi

27
Q

SPINAL CORD HISTOLOGY

  • anterior funiculus: between—— and——-
  • posterior funiculus: between——— and——-
  • white matter is divided into____,——-, and——- funiculus
  • grey matter has——- and——- horn. Also—— horn but only in ———,——-, and——- regions
A

grey matter; anterior median fissure

grey matter; posterior median septum

anterior; posterior; lateral

anterior ;posterior

lateral; thoracic; upper 2 lumbar; sacral

28
Q

Choroid plexus

-tufts of——- lined by——- cells

A

capillaries

ependymal

29
Q

Microglia acts as antigen presenting cells

T/F

A

T

30
Q

Microglia :
Retract their processes when they act like macrophages
Release neural proteases
Release oxidative radicals

T/F

A

T
T
T

31
Q

Multiple sclerosis is associated with

marked destruction of ependymal cells

Recruitment of CD4 and CD8 and T lymphocytes

Greater sex prediction in females than males

T/F

A

T
T
F

32
Q

Initial segment of the axon is

implicated in the genesis of epilepsy
Characterized by a higher density of voltage gated sodium channels that the remainder of the axons
The segment responsible for tay sach

T/F

A

T
T
F

33
Q

Parkinson’s affects

1% of those aged above 60

7% of those aged 80

And one of the most common neurological disorders

T/F

A

T
F(4)
T

34
Q

Which cells of the anterior pituitary are acidophils

A

Growth hormone

Prolactin (lactotrophs)

35
Q

Cushing syndrome is A condition that occurs from exposure to____ levels for a long time

A

high cortisol

36
Q

Oligodendrocytes are larger than Astrocytes

T/F

A

F

Smaller

37
Q

Oligodendrocytes lack internal filaments while Astrocytes dO

T/F

A

T

38
Q

Oligodendrocytes are migratory

T/F

A

T

39
Q

Which has denser cytoplasm?

Oligodendrocytes or astrocytes?

A

Oligodendrocytes

40
Q

Microglia are involved in homeostasis

T/F

A

T

41
Q

Microglia are the ____ cells of the spinal cord

A

Myeloid

42
Q

Accessory cuneatus nucleus:
Small in size
Large in size
Often suffer restricted lesions
Is the rostral equivalent of Clarke’s column
Relays proprioception from arm and neck to cerebellum

T/F

A
T
F
T
T
T
43
Q

Parkinson’s is an hyperkinetic disorder

T:F

A

F