Neuro Flashcards

1
Q

what are the receptors for the sympathetic and parasympathetic NS?

A

-sympa: epi,norepinephrine, dopamine which attach to ADRENERGIC receptors (alpha,beta)
-parasympathetic: acetylcholine attach to cholinergic (muscaritic , nicotinic)

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2
Q

what do anticholinergic meds do?

A

they stop the para system so it stops digestion and activates sympathetic

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3
Q

what are considered white matter? gray matter?

A

white matter are schwann cells which contain myelin, cell bodies are gray

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4
Q

where can you find csf?

A

its in the subarachnoid space

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5
Q

which meninge holds the cerebral arteries?

A

pia meninge

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6
Q

how does csf move?

A

lateral–> 3–>4th

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7
Q

what is nociceptive pain?

A

aching, stabbing, throbbing,pulsating

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8
Q

What type of pain is in the joints, muscles, and skin?

A

somatic pian

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9
Q

-unilateral, worsens w/movement
-N/V, photophobia
-triggers:alcohol, nitrates
-in women

A

migraines

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10
Q

what are the phases of migraines?

A

premonitory (days before), aura (right before), headache, recovery

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11
Q

cluster headaches

A

-in the eye, in men
-ptosis (dropping of eyelid),redeye, treating, stuffy nose

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12
Q

tension headache

A

-most common
-has to happen at least 15 days per month for 3 months

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13
Q

Myasthenia Gravis

A

-type II hypersensitivity AI that makes antibodies to acetylcholine receptors causing weakness in muscle
- symp: progressive weakness, ptosis, diplopia (seeing double),dysphagia, DIAPHRAGM STOPS WORKING

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14
Q

how do you test for myasthenia graves?

A

-tensilon test which tests positive if patient improves
-its anticholinergic which allows acetylcholine to accumulate allowing for a better contractioni

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15
Q

in cholinergic cris, there will be too much ___, causing ___ GI/GU, with __ HR,RR,BP. this will happen if a patient with the tensilon test ___.

A

-acetylcholine, increased , low, worsens

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16
Q

Guillain Barre syndrome

A

-demyelinating syndrome in PERIPHERAL NERVES
-starts from bottom to top, due to infection and will have resp infection or GI after
-symp: paresthesia, resp arrest
-treatment: ventilator, IVIG, plasmaphereis

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17
Q

Parkinsons

A

-chronic/progresive in basal ganglia,substantia nigra which produce dopamine
-this causes low levels of dopamine compared to acetylcholine
-symp: TRAD (tremors @ rest, rigidity, bradykinesia, postural disturbance)
-treatment: replace dop, anticholinergic drugs

18
Q

In a man with Parkinson’s, what will you see?

A

lewy bodies (clumps of protein)

19
Q

ALS amyotrophic lateral sclerosis

A

-neurodegenerative of motor neurons but NOT sensory/autonimic
-symp: weakness of muscles, normal intellectional function
-treat:2-5 yrs life expectactny , antiglutamtte

20
Q

Multiple sclerosis

A

-demyelinating in CNS; T helps mark myelin as foreign
-symp:paresthesia, hard to walk, loss of eye movement, impaired gait
-lesions present, high IgG
treatment: avoid extreme temp, immunosuppressants

21
Q

spinal shock

A

-COMPLETE loss of reflex, motor, sensor and autonomic below lesion
-regain everything, may take to 3 months

22
Q

Autonomy dysreflexia

A

-happens if injury is at T6 or above
-can’t empty bladder/rectum, high sympathetic NS= high BP, low HR
-symp: sweating

23
Q

what is the normal level of CSF?

A

5-15

24
Q

Increased Intercranial pressure

A

-symp:vomiting, sluggish, dilated pupils, cushing triad (high systolic, bradycardia , irregular respirations

25
Q

in children what type of hydrocephalus do they have?

A

noncommunicating which means theres an obstruction
in adults its due to lack of reabsorption

26
Q

epidural hematoma

A

period of lucidity with loss of unconsciousness due to meningeal arteries

27
Q

subdural

A

due to bridging veins, high mortality

28
Q

subarachnoid

A

-either aneurysm or trauma
RF: alchohol , HTN
-changes in pupil

29
Q

what are the Glasgow levels

A

13-15 mild
9-12 moderate
3-8 severe

30
Q

decorticate vs decerebrate

A

decorticate is flexion, bending hangs in
decerebrate is hand being extending out

31
Q

CVA stroke

A

-there are two types ischemic or hemorrhagic
-RF: hyperlipidemia, HTN, smokin, diabetes, a fib

32
Q

In ischemic ones, there are two, what are they?

A

-thromotic
-embolic: a fib, valvular prosthesis, MI

33
Q

what are the hemorrhagic ones?

A

due to HTN /ruptured aneurysms
-can have hemiparesis, aphsia

34
Q

Meningitis

A

-bacterial which enters through CSF or resp tract
-signs: fever, tachycardia, petechiae rash, photophobia
KERNIG : extend leg when sitting
BRUDZINSKI: flexion of legs and of neck

35
Q

bacterial vs viral

A

bacteria: turbid, protein is high, low glucose,
viral: clear, low protein, and normal glucose

36
Q

what are the classifications of seizures?

A

A.focal
-simple partial
-complex partial: losses consciousness, hallucinates
B. generalized
-absense, tonic clonic, myoclonic, atonic

37
Q

tonic clonic

A

tonic phase: back is arched, tense
clonic phase: limbs jerk
post ictal: awake but confused

38
Q

myoclonic

A

head/limb drop

39
Q

status epilepticus

A

seizures longer than 5 min
could lead to resp failure/death
give lorazepam
-aura means its coming NOW
-prodromal: early signs, few days before

40
Q

alzheimer’s

A

-will have amyloid plaques, and neurofibrillary tangles
-low acetylcholine
3 stages: in stage 2 theres sundown, loss of abstract thinking
-death happens to pneumonia/ pulmonary embolism
-TREATMENT: ACHE INHIBITORS