Cells, Tissue and Genetics Flashcards

1
Q

This packs and processes proteins

A

golgi apparatus

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2
Q

Synthesizes lipids/proteins

A

Rough ER

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3
Q

Digest cellular substances

A

Lysosomes

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4
Q

What are the 8 cellular functions

A

movement
conductivity
secretion
excretion
metabolic rxn
repirations
reproduction
communication

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5
Q

This transport moves from greater concentration to lower concentration. There are two types of this membrane transport.

A

Diffusion
There passive and facilitated diffusion

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6
Q

What molecules can pass through passive and which can’t?

A

Organic molecules can pass such as O2, CO2, and alcohol.
Protein and glucose CAN NOT pass through passive.
Glucose passes through facilitated

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7
Q

What are the 4 types of tissue?

A

epithelial, connective (binds organs and tissues), nerve (glia & neurons) and muscle (myocytes)

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8
Q

Definitions of cellular adaptations
1. it decreases in size cause it’s not in use
2. increase in size
3. increase in number of cells
4. A cell replaces another mature cell
5. there are abnormal changes in the size and shape

A

1.atrophy
2. hypertrophy
3.hyperplasia
4. metaplasia (seen in smokers airway)
5. dysplasia (an ex is cancer)

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9
Q

benign vs malignant

A

Benign tumors stay in place so they dont metastasize while malignant ones do

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10
Q

T or F
can tumors go from being benign to malignant?

A

True

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11
Q

What is this?
The cells are still in place, not able to move. this is considered early stage.

A

this is carcinoma in situ

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12
Q

Apoptosis vs Necrosis

A

apoptosis is when the cell programmed its death while necrosis is always a pathological death, meaning it shouldn’t have died

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13
Q

What are examples of too much apoptosis?

A

Alzheimers, parkinsons and ALS

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14
Q

T or F
There are 24 pairs of chromosomes

A

False, there are 23 pairs which include 1 pair of sex chromosomes

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15
Q

What is the basic unit of inheritance ?

A

genes

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16
Q

What is the process of going from DNA to Proteins?

A

it includes two processes
transcription : DNA -> RNA (inside nucleus)
translation : RNA -> proteins (inside cytoplasm)

17
Q

Autosomal dominant

A

this is when both female and male are affected equally

18
Q

Marfan syndrome

A

ex of autosomal dominant
- it’s a disease of the connective tissue causing long arms/legs
-it causes ocular (myopia, retinal detachment), skeletal (hyper mobility) and cardiovascular abnormalities.

19
Q

Autosomal Recessive

A

this is when you need both of the little letter to have the disease. if you only have one, then you are a carrier

20
Q

Cystic fibrosis

A

ex of autosomal recessive
- causes think mucus in GI and respiratory tract.
-happens due to decrease in Cl transport

21
Q

What organs does cystic fibrosis affect?

A

sinuses, lungs, skin, liver, pancreas, intestines, and reproductive

22
Q

Phenylketonuria PKU

A

an ex of autosomal recessive
-caused by a defect in amino acid metabolism; excess of phenylalanine
-causes mental retardation, fair skin/hair and eczema

23
Q

Tay Sachs disorder

A

an ex of autosomal recessive
- excess of glyolipids in brain; lysosomes aren’t working
-causes seizures & blindness in ages 2-5
they dont last long with disease
no treatment but genetic screening can be done

24
Q

T or F
Y linked inheritance is more common than x linked

A

FALSE; x linked is more common

25
Q

Color blindness

A

happens in males because they dont have a second X to compensate for the bad X
it’s an x linked recessive disorder

26
Q

Chromosomal disorders happen because of what?

A
  • radiation/chemicals
  • viral infections
27
Q

Trisomy 21

A

three chromosomes at spot 21 instead of 2
happens because there was a failure to separate during oogenesis/spermatogenesis

28
Q

Turner syndrome

A
  • happens to girls
    -they are missing the second X which causes them to not develop secondary sex characteristics
    -causes: short statue, webbing of neck, absent ovaries and coarctation of aorta.
29
Q

What gene and chromosome is mutated in cystic fibrosis?

A

The CFTR gene on chromosome 7