neural tube defects Flashcards

1
Q

how can neural tube defects be prevented

A

folic acid

-400micrograms/day, 1 month prior to conception

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2
Q

level of function in spina bifida patients at L3 level or lower

A

community abulators

-walk indoors and outdoors for most activites

-wheelchairs may be sued for longer trips

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3
Q

level of function in spina bifida patients at L3 or mid lumbar

A

household ambulators

-walk indoors and transfer to hweelchair for community use and most outdoor activity

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4
Q

level of function in spina bifida patients at L1-L3

A

nonfunctional ambulators

-walk as part of therapy session or. using orthotic device

-use wheelchair for most needs

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5
Q

level of function in spina bifida patients at higher than L1

A

nonambulators
-wheelchair for all use

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6
Q

define a myelomeningocele

A

outpouching of spinal cord and voering through defect in posterior elements of vertebral arches
d

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7
Q

what is likely to be affectedin myelomeningocele 2

A

cervical cord

brainstem

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8
Q

associated problems with myelomeningocele 5

A

mobility

sensation

bowel and bladder function

hydrocephalus

specific learning problems( some individuals only)

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9
Q

define hydrocephalus

A

excessive volume of CSF fluid in ventricualr system

-caused by imbalance between CSF production and absoprtion

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10
Q

symptoms of hydrocephalus 4

A

headache

N+V

papilloedema

coma (severe cases)

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11
Q

features of headache in hydrocephalus

A

worse in morning

when lying down

during valsalva

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12
Q

what produces CSF

A

specialised ependymal cells

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13
Q

where is CSF produced

A

in choroid plexus. of the ventircles of the brain

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14
Q

where is CSF absorbed

A

arachnoid granulations

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15
Q

features of hydrocephalus in children and why 1

A

increase in head circumference - as the skull sutures havent fused yet
-open fontanelle buldges and beocmes tense

-

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16
Q

feature of severe hydrocecphalus in children and why 1

A

failure of upward gaze
-sunsetting eyes

-compressoin of superior colliculus of the midbrain

17
Q

types of hydrocephalus 2

A

obstructive - non communicating

non-obstructive - communicating

18
Q

pathophys of obstructive hydrocephalus

A

structural pathology blocking flow of CSF

dilation of ventricular system

19
Q

causes of obstructive hydrocephalus 3

A

tumours

acute haemorrrhage (SAH or intraventricular haemorrhage)

developmenetal abnormaliteis -aqueduct stenosis

20
Q

pathophys of non-obstructive hydrocephalus 1

A

imbalance of CSF production and absoprtion

21
Q

causes of non-obstructive hydrocephalus 3

A

increased production og CSF
-choroid plpexus tumour (v rare)

fialure of reabsorption at arachonid granulations (more common)
-meningitis
-post-haemorrhagic