Henoch Schonlein Purpura

Question 1

define Henoch Schonlein Purpura

Answer 1

IgA mediated small vessel vasculitis

-has some overalp with IgA nephropathy (bergers disease)

Question 2

who gets Henoch Schonlein Purpura

Answer 2

usually seen inchildren following infection

Question 3

basic pathophys of Henoch Schonlein Purpura

Answer 3

deposits of IgA containg immune complexes in capillaries, arterioles and venules

Question 4

presenation of Henoch Schonlein Purpura 4

Answer 4

PALPABLE PURPURIC RASH

abdo pain

polyarhtitis

featues of IgA nephropathy
-haematuira
-renal failure

Question 5

investigatoins for Henoch Schonlein Purpura 7

Answer 5

FBC (platlets may be raised)

CRP

ESR

urinalsysi

BP

abdo USS

biopsy- renal or skin - shows IgA deposistion -storngly supportive

Question 6

management of Henoch Schonlein Purpura 4

Answer 6

analgesia for athralgia

nephropathy- generally supportive
-monitor renal function
-urinalysis
BP

monitor for intussusception