breast milk jaundice Flashcards
important point about jaundice in first 24 hrs after birth
always pathological
causes of jaundice in the first 24hrs after birth 4
rhesus haemolytic disease
ABO haemolytic disease
hereditary spherocytosis
glucose-6-phosphodehydrogenase
causes of jaundice in neonates from 2-14 days
usually physiological
combination of factors:
-more red blood cells
-more fragile red blood cells
-less developed liver function
-MOST COMMONLY SEEN IN BREASTFED BABIES
when is a prolonged jaundice screen in a newborn done 2
still signs of jaundice after 14 days
or
21 days in a premature baby
what are the components of a prolonged jaundice screen in a newborn 6
conjugated and unconjugaretd bilirubin
-most important - as can indicate a riased conjugated buiklirubin which couldbe due to biliary atresia which needs immediate surgical intervention
direct antiglobulin test (Coombs test)
TFTs
FBC and blood film
urine and MC&S and reducing sugars
U&Es and LFTs
causes of prolonged jaundice in a newborn 6
biliary atresia
hypothyroidism
galactosaemia
urinary tract infection
prematurity
congential infections eg CMV or toxoplasmosis
define breast milke jaundice
Breast milk jaundice most often occurs in the second or later weeks of life and can continue for several weeks. While the exact mechanism leading to breast milk jaundice is unknown, it is believed that substances in the mother’s milk inhibit the ability of the infant’s liver to process bilirubin.
high conncentrtaitons of beta-glucoronidase-> increase in intestinal absorption of unconjugated bilirubin
Jaundice is most common in breastfed babies
treatment for breast milk jaundice 1
phototherapy
can also use temporary subsition for fomula milk or stop breastfeeding breifly
treatment for breast milk jaundice 1
phototherapy
can also use temporary subsition for fomula milk or stop breastfeeding breifly
