Nervous System Flashcards
-Brain and Spinal cord compose the _____
CNS
The two principal cell types of nervous tissue are?
Neurons and Neuroglia
“excitable cells that transmit electrical signals” what are these?
Neurons
How many types of Neuroglia cells are there?
six
Are astrocytes and ependymal cells neuroglia cells?
Yes
Are microglia and oligondendrocyres neuroglia cells?
Yes
Are schwann and satellite cells neuroglia cells?
Yes
Which neuroglia cell is the most abundant?
Astrocytes
“Projections surround capillaries, neurons, synaptic endings, forming the blood/brain barrier” Which neuroglia cell is this?
Astrocytes
What do astrocytes regulate?
They regulate components of the brain fluids
Are neuroglia cells that produce electricity?
No, they are supporting cells. Only the neuron does
Astrocytes exchange ______ and _____
Nutrients and waste
Which neuroglia cell has an exchange of nutrients and waste?
Astrocytes
Do astrocytes bind to neurons?
Yes
Which neuroglia helps determine capillary permeability?
Astrocytes
Which neuroglia cell has the job of the guiding migration of young neurons?
Astrocytes
Do astrocytes help the neuron by processing information in the brain?
Yes
This neuroglia cell is found in the lining of ventricles of the brain and central canal of the spinal cord. Which neuroglia cell am I?
Ependymal Cells
The choroid plexus (blood venues surrounded by ependymal cells) in ventricles secrete _______ ______
Cerebrospinal fluid
Cilia assist in the movement of cerebrospinal flood in which neuroglia cell?
Ependymal cells
Ependymal cells range in shape from _____ to ______
squamous to columnar
Can ependymal cells be ciliated?
Yeah, sometimes
Microglia are like _______
Macrophages
“Macrophages that respond to infection in the CNS” What am I?
A microglia cell
Which neuroglia cell is involved in phagocytize(ing)
Microglia
Which cells in the CNS are defensive cells?
Microglial
Which neuroglia cell provide the myelin sheath for neurons in the CNS?
Oligodendrocytes
Oligodendrocytes insulate ____ in the CNS
Axons
_______ help propagate action potentials in the CNS
Oligodendrocytes
How many oligodendrocytes does it take to myelinate multiple axons?
ONE
Which neuroglia cell surrounds the neuron cell bodies in the PNS?
Satellite Cells
Schwann cells are also called _______
neurolemmocytes
How many schwann cells does it take to myelinate one axon?
ONE
Schwann cells provide the _____ ____ for neurons in the PNS
Myelin Sheath
Just like Oligodendrocytes, this neuroglia cell helps propagate action potentials in the PNS
Schwann cells
_____ cells support and provide nutrition for sensory neuron cell bodies
Satellite Cells
Dendrites are _____, ______, and diffusely branches
Short, tapering
Which part of a neuron is the receptive region?
Dendrites
______ convey electrical signals toward the cell body as graded potentials
Dendrites
______ convey electrical signals toward the cell body as graded potentials
Dendrites
There is ____ axon per cell and it arises from the ____ ____
one; axon hillock
The ______ has numerous terminal branches
Axon
the axon has _____ _____ branches
numerous terminal
The axon has _____ _____ terminals, also called _______
knoblike axon terminals; boutons
The axon releases __________ to excite or inhibit other cells
Neurotransmitters
What is the function of an axon?
Generates and Transmits nerve impulses away from the cell body
Axons generate and transmit nerve impulses (___ ___) away from the cell body
Action Potentials
Graded potentials can be either high, low, or built up. True?
Yes
Molecules and organelles are moved along axons by motor molecules in two directions.
- ______
- ______
Anterograde and Retrograde
Molecules and organelles are moved along axons in ______ direction when they go toward the axonal terminal
Anterograde
Molecules and organelles are moved along axons in ______ direction when they go toward the cell body
Retrograde
The _____ ____ is a segmented protein-lipoid sheath around most or large diameter axons
Myelin Sheath
The function of the myelin sheath is to protect and _____ ____ the eaxon
Electrically insulate
The myelin sheath increases the speed of ____ _____ _____
Nerve impulse transmission
The ______ is the peripheral bulge of Schwann cell cytoplasm
Neurilemma
___ _____ wrap many times around the axon
Schwann cells
Nodes of Ranvier are myelin sheath _____ between adjacent schwann cells
Gaps
Where can axon collaterals emerge?
The nodes of ranvier
Which nerve fibers are unmyelinated? Thick or thin?
Thin
Myelin sheaths in the CNS are formed by processes of ___________
Oligodendrocytes
Are nodes of ranvier present in Myelin sheaths of the CNS?
Yes
_____ matter are dense collections of myelinated fibers
White
____ matter are mostly neuron cell bodies and unmyelinated fibers
Gray
Types of neurons
- _______
- ________
- ________
Multipolar neurons, bipolar neurons, and pseudo unipolar neurons
Finish slide 50
:)
Most motor neurons are ______ neurons
Multipolar neurons
Bi polar neurons have one _____ and one _____
dendrite and axon
Multipolar neurons have many _____ with a single _____
Dendrites and a single axon
Which type of neuron has many dendrites and a single axon?
Multipolar neurons
Which type of neuron has one dendrite and one axon?
Bi polar neurons
_____-_____ nuerons have a single process EXTENDING from the cell body
Pseudo-Unipolar neurons
Two main types of ion channels?
- _______
- ________
Leakage non gated channels (always open) and gated channels
Three types of gated channels?
Chemically, voltage-gated, and mechanically gated channels
_____ _____ channels open with binding of a specific neurotransmitter
Chemically gated
_____ _____ channels open and close in response to changes in membrane potential
Voltage-gated
_______ _____ channels open and close in response to physical deformation of receptors
Mechanically gated channels
When gates channels are open, ____ ____ quickly across the membrane along their electrochemical gradients
Ions diffuse
IPSPS causes the neuron to _____ ____
shut down
10 EPSP + 5 IPSP = 5 EPSP. Is there action potential?
yaaasssss
Biogenic amines include _______ and _______
Catecholamines and indolamines
Biogenic amines play roles in ______ ______ and the _______ clock
emotional behaviors and the biological clock
Catecholamines include _______, _______(NE), and __________
dopamine, norepinephrine, and epinephrine
Indolamines include ______ and ______
serotonin and histamine
Most neurons make two or more ________, which are released at different ______ ________
neurotransmitters; stimulation frequencies
GABA, Glycine, Aspartate, and glutamate are all ____ _____
amino acids
Which two amino acids are inhibitory?
GABA and Glycine
Which two amino acids are excitatory?
Aspartate and Glutamate
The three main peptides are _______, ______, and __-________
Substance P, Endorphins, and gut-brain peptides
Substance P is a mediator of _____ signals
Pain
Endorphins, a peptide, act as natural ______,
opiates
Do ions diffuse quickly when chemical concentration gradients go from higher to lower concentration? or lower to higher concentration?
Higher concentration to lower concentration
Ions can diffuse quickly when _____ _____ are open
gated channels
Ions diffuse quickly across the membrane along their electrochemical gradients, and also along electrical gradients toward _____ _____ charge
opposite electrical charge
Ion flow creates an ____ _____ and voltage changes across the membrane
electrical current
“Approximately -70 mV in neurons” Does this mean resting membrane potential is occurring?
Yes
Resting membrane potenital is equal to how many mV in neurons?
-70
Resting membrane potential is generated by differences in _____ makeup of ____ and _____
ionic makeup of ICF and ECF
ICF has a lower concentration of ___ and ____ than ECF
Na+ and Cl-
ICF has a higher concentration of ___ and negatively charged proteins (___) than ECF
K+ and (A-)
____ has a lower concentration of Na+ and Cl- than ____
ICF; ECF
___ has a higher concentration of K+ and negatively charged proteins (A-) than ____
ICF; ECF
In resting membrane potential, the membrane is slightly permeable to ___ (through leakage channels)
Na+
In resting membrane potential, the membrane is 75 times more permeable to ___ (through leakage channels)
K+
When is the membrane freely permeable to Cl-?
Resting membrane potential
During Resting membrane potential, the negative interior of the cell is due to much greater diffusion of ____ out of the cell than Na+ diffusion into the cell
K+
Resting membrane potential, _____-_____ pumps stabilize the resting membrane potential by maintaining the concentration gradients for Na+ and K+
Sodium-Potassium pumps
Membrane potential changes when ________ of ions across the membrane change
concentrations
Membrane potential changes when ______ of the membrane to ions changes
permeability
Changes in membrane potential are signals used to _____, _____, and send information
receive, integrate
In membrane potential, there are two types of signals. ______ potentials and _____ potentials
Graded and Action
_____ potentials are responsible for incoming ____-_____ signals
Graded potentials are responsible for incoming short-distance signals
_____ potentials are responsible for ___-____ signals of axons
Action potentials are responsible for long-distance signals of axons
A graded local potential is when stimulus causes Na+ ______ to open for a short period on the ____ body and _____ of the nerve cell
channels; cell body and dendrites
In a graded local potential, open channels allow Na+ to move into the ____, causing a change in the membranes electrical potential
call
“EXCITATION” causes channels to open in a graded local potential. Excitation stands for…..
Excitatory Post Synaptic Potential
“INHIBITION” in a graded local potential: stimulus causes channels to close. Inhibition stands for…
Inhibitory Post Synaptic Potential
During changes in Membrane Potential, Depolarization occurs, which is a reduction in _____ _____ ( toward zero)
membrane potential
During depolarization, the inside of the membrane becomes less _____ than the resting potential
Negative
One change in the membrane potential is Hyperpolarization, which is an _____ in membrane potential (away from zero)
Increase
During hyper polarization, the inside of the membrane becomes more _____ than the resting potential
negative