Neoplasm & cancer Flashcards

1
Q

The term carcinoma refers to a tumour of the …?

Fatty tissue
Epithelial tissue
Connective tissue
Blood

A

Epithelial tissue

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2
Q

Which one of the following is false about benign tumours !

Tissue damage results from compression of adjacent structures

Benign tumours in the brain are considered critical

They are made up of undifferentiated, non-functional cells that do not appear organised

They expand but do not spread

A

They are made up of undifferentiated, non-functional cells that do not appear organised

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3
Q

Angiogenesis is the process of . . . ?

The development of new capillaries in the tumour

Metastasis of malignant cells by blood
cells

Metastasis of malignant cells by lymphatic vessels

Breaking down protein or cells

A

The development of new capillaries in the tumour

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4
Q

Choose:

Humans have a total of 44 chromosomes

Humans have 21 pairs of autosomes and two pairs of allosomes

Humans have a total of 46 chromosomes in addition to the two sex chromosomes

Humans have 22 pairs of autosomal and two allosomes

A

Humans have 22 pairs of autosomal and two allosomes

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5
Q

Marfans syndrome follows which type of inheritance pattern?

X- linked recessive inheritance pattern
Autosomal dominant inheritance pattern
X-linked dominant inheritance pattern
Autosomal recessive inheritance pattern

A

Autosomal dominant inheritance pattern

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6
Q

What is the correct name for the protein affected by cystic fibrosis?

Chloride facilitated transport protein
Cystic fibrosis transport protein
Cystic fibrosis transmembrane protein
None of above

A

Cystic fibrosis transmembrane protein

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7
Q

Which statement best describes the difference between haemophilia A and haemophilia B

See photo

A

Correct answer

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8
Q

Duchenne Muscular dystrophy is a X-Linked recessive genetic disease. If a female who carries one affected allele had children with an unaffected male which state mental would be correct about their children ?

A

There is a 0% chance that any female children will inherit DMD and a 50% chance that any male children will inherit DMD

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9
Q

What does grade refer to ?

A

How close the tumour resembles the original cells

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10
Q

Is a benign or a malignant tumour low grade & why is that?

A

Benign as it closely resembles the cells of origin

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11
Q

Are malignant tumours differentiated or non-differentiated ? Ans what grade are they high or low ?

A

Non-differentiated and high grade

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12
Q

What is a primary and secondary tumor ??

A

Primary: main tumour
Secondary: secondary sites after the tumour metastasizes

E.g: primary; tumour in the colon may metastasize via blood to the liver !
Multiple metastatic tumours will grow occupy space leading to hepatocyte injury ultimates liver failure and death
This can occur even when the primary tumour is removed

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13
Q

What does the stage of a malignant tumour mean ?

A

How far the tumour has progressed !

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14
Q

Where in the bodily cells would you find a papilloma (polyp)

Connective tissue surface
Epithelial cell surface
Glandular cell surface

A

Epithelial surfaces

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15
Q

Are papilloma tumours that are found on the epithelial surfaces benign or malignant ?

A

Benign tumour that is caused by the human pailloma virus (HSV)

E.g Polyps; usually a term to refer to epithelial lesions that project from the surface into the Lumen

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16
Q

The suffix -Oma means that it’s what benign or malignant ?

A

Benign

17
Q

A benign tumour arising from the glandular epithelium is called what ?

Adenoma
Angioma

A

Adenoma

18
Q

A chondroma is a benign tumour in the …

Blood vessels
Cartilage
Liver
billiary duct system

A

Cartilage

19
Q

Tumours with the suffix starting with

Adreno Are located where

Cartilage
Lymph vessels
muscle
Gland

A

Gland

20
Q

Tumours with the suffix starting with

Angio are where?
Hint: not specific

A

Vessels

21
Q

Tumours with the suffix starting with

Chondro are found where ?

A

Cartilage

22
Q

Tumours with the suffix starting with

Hemangio are where ? (Specific)

Blood vessels
Heart valves
Liver tubules

A

Blood vessels

23
Q

What are the 3 classifications of malignant tumours ?

Hint: carβ€”-

A

Carcinoma
Sacroma
Leukemia/lymphoma

24
Q

Carcinoma is where:

Connective tissue
Epithelial tissue
Glandular epithelium

A

Epithelial tissue

Any malignant tumour arising from surface, glandular, or parenchymal (organ) surface

25
Q

Sacroma

Connective tissue
Epithelial tissue
Glandular epithelium

A

Connective

26
Q

Leukemia/lymphoma from:

Connective tissue
Blood cells and precursors
Epithelial tissue
Glandular epithelium

A

Blood cells and precursors

27
Q

Malignant tumours are further classified into what 2 catogries:

Connective
Glandular
Epithelial
Infective

A

Glandular
Epithelial

28
Q

Since the cancers from WBCs are no solid but proliferate within bone marrow what does this do to the normal blood forming cells ? Which causs…

A

Crowds them out !!

29
Q

The neoplasmic cells spill out into the normal circulating volume when the over crowd the bone marrow however decide to sit in two places instead of circulating. Where are these places !!

A

Spleen and lymph nodes

Then the term lyphoma is used

30
Q

Where are melanomas derived from?

A

Melanocytes

31
Q

Neoplasms that develop in these cells (melanocytes) are called what …

A

Benign nevi

They’re malignant tho !!

32
Q

What is a Tetroma?
Hint: 🦠

A

Germ cell derived tumour of Multiple tissue types and can be benign ir malignant.

33
Q

For pediatrics what’s the suffix that’s used for malignant neoplasms

-oma
-blastoma
-Sacroma

A

Blastoma

34
Q

What is neohroblastoma also called ?

A

Wilms tumour