Neoplasia Flashcards
define neoplasia
new growth
3 general characteristics of neoplasia
- behave as parasites and compete with normal tissue for food and oxygen
- tumor has a certain degree of anatomy and increases without regard for the condition of the host. not under body control.
- neoplasms are crtically dependent on host blood supply
define hyperplasia
increase in number of cells
define metaplasia? example?
substitution of one cell for another cell that is fragile
example: person who is a smoker: respiratory passage
define dysplasia? another name for this?
loss of uniformity of cells meaning they don’t all look the same
- cells have abnormal cell size and shape
- may not revert to normal
- also known as pre-cancerous cells
what is dysplasia due to?
prolonged irritation
define anaplasia? another name?
proliferation of abnormal cells
- no body control
- also known as cancer cells
characteristics of benign tumors
- well-differentiated: some cells look like normal tissue
- functional cells: cells still do their job
- slow growing: get bigger slowly
- mitotic figures: normal
- encapsulated: tumor is in pouch and separated from rest of body
- tumor cells don’t spread
malignant tumor characteristics
- poorly differentiated; not normal
- non-functional cells
- rapid growth
- abnormal mitotic figures
- not capsulated
- tumor cells spread to the rest of the body
what is something tumor cells lack?
cohesiveness
-put together in a test tube, they aren’t drawn together. which is the reason for papanicolan
define metastasis
refers to the spread of a cancer from its primary location to other locations in the body
what are the 4 possible ways cancer can spread?
- seeding in body cavities: new tumors formed in body cavity such as colon cancer or intestinal cancer
- direct transportation: operation to remove a tumor and tumor cells get transported to different part of body by manipulation
- lymphatic permeation: most common way
- transport through blood vessels: not very common
what is the major cause with cancer?
metastasis
define carcinogens?
things that cause cancer
what are the 3 causes of cancer?
- chemicals: preservatives in cured meat, smoking, tobacco, some hormones
- viruses: HPV, Epstein-Barr, Hepatitis B
- Radiation: UV from the sun