Neonatal Immunity Flashcards
Animals w/ long gestation periods have ______ immune systems at birth
Fully developed (but can’t function at adult level for several wks)
Animals w/ short gestational periods have ______ immune systems at birth
Less developed
When do B lymphocytes and antibodies appear in fetal development
- B lymphocytes: soon after spleen & lymph node development
- not antibodies until late fetal life
When are fetal pig neutrophils capable of phagocytosis
90 days post-conception
Serum of newborn animals is deficient in ________, causing them to be more susceptible to disease
Complement
Best time to first vaccinate puppies
8-12 weeks after birth
How to treat 2 day old foal w/ IgG level of 200 md/dl
IgG intravenously
Predominant Ig in colostrum of most domestic animals
IgG
In fetal calf, what organ develops first
Thymus
List tests used to diagnose failure of passive transfer
- SNAP test for foals
- zinc sulfate turbidity
- latex agglutination
- single radial/mansini immunodiffusion
When do b lymphocytes and antibodies develop
- b lymphocytes: soon after dev.
- antibodies: late fetal life
When are fetuses able to respond to antigens
Right after lymphoid organ dev.
In fetal pigs, when are neutrophils capable of phagocytosis
90 days post conception
Infecting pregnant ewes at 50 days of pregnancy w/ bluetongue virus will do what to fetal lambs
Cause severe disease
If 100 day pregnant ewes are infected w/ bluetongue virus, the fetus will
Only have mild disease
