Hypersensitivities 3&4 Flashcards

1
Q

Are there any hypoallergenic dogs

A

No

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2
Q

Pet allergies activated by hair on pet?

A

No

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3
Q

Hay fever and pet allergy symptoms similar?

A

Yes

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4
Q

Reptiles common pet allergy cause?

A

No

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5
Q

Can you have allergy symptoms even if pet isnt in room?

A

Yes

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6
Q

Pet allergy is a form of allergic rhinitis

A

Yes

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7
Q

3 steps of delayed hypersensitivity rxn

A
  • sensitization
  • repeat exposure
  • immune (hypersensitivity)
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8
Q

Four sensitivity types

A
  • 1: anaphylactic

-2: cytotoxic

-3: immune complex

-4: delayed

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9
Q

How do mast cells degranulate? List their 2 impacts

A
  • antigen binds to IgE receptors on mast cell, causes release of mediators
  • affects: acute inflammation and systemic effects
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10
Q

Skin contact w/ allergen is not a common cause of urticaria

A

True

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11
Q

Flea allergy dermatitis causative allergen and hypersensitivity type

A
  • Ctenocephalides felis
  • type 2
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12
Q

Canine AD caused by

A

Dermatophagoides pteronyssinus and D. Farinae (Der f15)

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13
Q

Classical type i hypersensitivity rn

A
  • Fc epsilon RI= hi affinity receptor for Fc region of IgE
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14
Q

Poststreptococcal glomerulonephritis

A
  • rapid decrease in kidney function after strep infection
  • type 3
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15
Q

Immune complex mediated hypersensitvity rxn steps (type 3)

A
  • immune complexes deposited in organs
  • complement activated
  • neutrophils degranulated
  • enzymes released and damage cells
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16
Q

Inflammatory polyarthritis (type 3)

A
  • can be erosive or non erosive
  • examples: rheumatoid arthritis and greyhound/feline progrssive polyarthritis
  • clinical signs: lameness, multiple jt pain, jt swelling, fever, malaise, anorexia
17
Q

Diagnosis and treatment of polyarthritis

A
  • diagnosis: x-rays, biopsy, arthrocentesis, serologic testing
  • treat: anti-inflammatories, chemotherapy agents
18
Q

Systemic lupus erythematosus

A
  • animals immune system attacks own tissue

Type 3

19
Q

Tests for type 4 hypersens.

A
  • tb skin test
  • palpebral test
  • caudal fold test
  • comparative cervical test: avian/bovine