B Cell Activation And Humoral Immunity Flashcards
Membrane receptor of B cells
- BCR
- function: to act as receptor for antigens
Lymph node position of B and T cells
- B: Outside
- T: inside
Connections of B & T Cells
- B: connects to antigens directly on surface of invading bacteria or viruses
- T: connects to antigens on outside of infected cells
Tissue distribution of B cells
Germinal ctrs of lymph nodes
Spleen
Gut
Respiratory tract
Subcapsular & medullary cords of lymph nodes
Tissue distribution of T cells
Parafollicular area of cortex in nodes
Periarteriolar area in spleen
Life span of B & T Cells
- B: short
- T: long
Surface antibodies of B & T Cells
- B: present
-T: absent
B or T cells secrete antibodies
B cells
B cells form
Humoral/antibody-mediated immune system (AMI)
T cells form
Cell-mediated immune system (CMI)
Conc. of T cells in blood
80% Lymphocytes
Cd4>CD8
B cell conc. in blood
20%
Do B & T Cells move to site of infection
- B: no
-T: yes, lymphocytes
Do B & T Cells have inhibitory effects on immune system
- B: no
- T: yes, suppressor cells
Feline leukemia & feline immunodeficiency virus increase risk of
Developing lymphoma