Introduction Flashcards
Immunity
Body’s ability to resist infection
Bone marrow
- red marrow: blood stem cells that can become red blood cells, leukocytes, and platelets
- yellow marrow: mostly fat
Functions of spleen
- stores blood
- filters blood (by removing cell waste and getting rid of old/damaged cells)
- makes leukocytes
- makes antibodies
- maintains fluid levels
Animal with similar immune system to humans
Pigs (>80%)
Do all birds have IgY in yolk?
Yes
Who discovered IgY antibodies in ostrich yolks
Dr. Yasuhiro Tsukamoto
What animal has the most powerful immune system?
Ostriches
Ostriches produce antibodies within _____ weeks of exposure to antigens
2
Ostriches’ IgY are _____ heat sensitive and _____ acid resistant compared to other avians
Less; more
Von Behring (1901)
Discovery of serum antibody
Koch (1905)
Immune response in tuberculosis
Brodet (1919)
Complement
Edelman and Porter (1972)
Antibody structure
Location and function of harderian gland
- location: behind eyes
- function: produces lacrimal fluid
- is a peripheral lymphoid organ
Bursa fabricious
- unique organ to birds
- primary lymphoid organ for B cell differentiation, maturation, and development
Cecal tonsils
- location: cecum-rectum junction
- largest lymphoid collections of avian GALT
- function: elicit protective immune response against bacterial and viral pathogens
Most bony fish do/do not have functional bone marrow
- do not
Where is heamopoeisis located in most bony fish
- spleen
- kidney
- intestimal submucosa
- thymus