narcotic analgesics and antagonists

Question 1

action of narcotic analgesics

Answer 1

bind to opiate receptors in CNS
agonists of opioid peptides (endorphins)
results in alteration to perception of pain

Question 2

adverse effects of narcotic analgesics

Answer 2

RESPIRATORY DEPRESSION, lightheadedness, constipation, nausea/vomiting

Question 3

contraindications of narcotic analgesics

Answer 3

head injury or increased ICP, hypoxia, hepatic impairment

Question 4

action of narcotic antagonists

Answer 4

binds to opioid receptors with higher affinity than agonists but do not activate the receptors blocking the body from responding to opiates and endorphins

Question 5

when are opioid antagonists used

Answer 5

opiate overdose

Question 6

adverse effects of narcotic antagonists

Answer 6

acute opioid withdrawal - -pain, tachycardia, HTN, fever, sweating, ABD cramps, diarrhea, nausea, vomiting, agitation, and irritability

Question 7

contraindications of narcotic antagonists

Answer 7

coronary artery disease, pregnancy