antihypertensives PG 882 Flashcards

1
Q

what is considered normal blood pressure

A

<120/<80

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2
Q

what is considered elevated blood pressure

A

120-129/80

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3
Q

what is considered stage 1 hypertension

A

130-139/80-89

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4
Q

what is considered stage 2 hypertension

A

> 140/>90

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5
Q

what is step 1 of treating hypertension

A

lifestyle changes

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6
Q

what is stage 2 of treating hypertension

A

thiazide diuretic, ACE inhibitor, ARB, or CCB (use 1)

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7
Q

consider using which type of medication in African American patients due to increased risk of angioedema

A

use ARB instead of ACE inhibitor

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8
Q

what is stage 3 of treating hypertension

A

increase dose of drugs or combine two drugs

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9
Q

what is step 4 of treating hypertension

A

combine 2-3 of step 3

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10
Q

what are the different classes of antihypertensive medication

A

ACE inhibitors/angiotensin II antagonists (ARBs)
diuretics
calcium channel blockers
beta blockers

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11
Q

action of ACE inhibitors

A

lower BP by dilating arterial blood vessels

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12
Q

what medication is used in first line treatment of HTN in patients with DM

A

ACE inhibitors

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13
Q

adverse effects of ACE inhibitors

A

postural/orthostatic hypotension
angioedema (in african american patients)
dry hacking cough

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14
Q

contraindications of ACE inhibitors

A

renal or hepatic disease

electrolyte imbalance

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15
Q

action of calcium channel blockers

A

causes peripheral vasodilation

inhibits calcium from getting in to muscle cells to cause contraction

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16
Q

what are the 2 categories of calcium channel blockers

A

dihydropyridines - little to no negative effect on cardiac contractility or conduction

non-dihydropyridines - greater depressive effect on cardiac conduction and contractility

17
Q

adverse effects of dihydropyridines

A

headache, lightheadedness, flushing, peripheral edema

18
Q

adverse effects of non-dihydropyridines

A

constipation, bradycardia, heart failure, heart block

19
Q

contraindications of dihydropyridines

A

hepatic impairment, severe coronary artery disease, and sever aortic stenosis

20
Q

contraindications of non-dihydropyridines

A

second or third degree heart block, acute MI, congestive heart failure

21
Q

action of beta blockers

A

compete with adrenergic neurotransmitters (epi and norepi) for adrenergic receptor sites

22
Q

where are beta1 receptor sites usually located

A

in the heart

23
Q

where are beta2 receptors usually located

A

bronchial and vascular smooth muscle and the uterus

24
Q

which beta receptors do selective beta blockers work on

A

beta1

25
Q

which beta receptors do non selective beta blockers work on

A

beta1 and beta2

26
Q

adverse effects of beta blockers

A

orthostatic hypotension, bradycardia, bronchospasm

27
Q

contraindications of beta blockers

A

sinus bradycardia, heart block, hypotension