Antihyperlipidemic PG 887 Flashcards
This subclass of diuretics works by increasing excretion of sodium and chloride by inhibiting the reabsorption of these ions in the distal proximal tubules and the loop of Henle.
Loop Diuretics
This subclass of diuretics increases the density of the filtrate in the glomerulus; prevents reabsorption of water; salt and chloride follow water.
Osmotic Diuretics
This subclass of diuretics decreases the reabsorption of sodium and water in the kidney and increases potassium retention:
Potassium Sparing
This subclass of diuretics decreases the absorption of sodium and chloride ions in the kidney.
Thiazide
This subclass of diuretics inhibit the action of carbonic anhydrase which lead to the excretion of sodium, potassium, bicarbonate and water:
Carbon Anhydrase Inhibitor
this class of antihyperlipidemic is used for open angle glaucoma (preoperatively to lower intraocular pressure), Edema due to CHF, cirrhosis of the liver, and or renal failure, and hypertension
Diuretics
the adverse effects of this antihyperlipidemic causes fluid and electrolyte imbalance, orthostatic hypertension (syncope), and arrhythmias:
Diuretics.
When is the best time of day to administer diuretics?
administer early in the day to prevent nocturnal diuresis and disturbances of sleep.
patient management of this antihyperlipidemic includes needing to void often in the first few weeks and need to monitor to replace electrolytes (in particular potassium)
Diuretics
Contraindications/warnings/cautions for diuretic use:
sensitivity to sulfonamides
kidney disease
electrolyte imbalance
uncontrolled arrhythmias
this example of a subclass of diuretics is used for the management of idiopathic (or benign) intracranial hypertension and elevated pressure.
Carbonic Anhydrase Inhibitors e.g. Acetazolamide: Diamox
this example of a subclass diuretic is used for management of edema associate with CHF, cirrhosis of liver, renal disease or acute pulmonary edema. (MAY CAUSE HYPOKALEMIA)
Loop Diuretics
this example of subclass diuretics may be used as additional therapy for the management of hypertension
Potassium sparing diuretics
this example of a subclass of diuretics is one of the first line indication for managing hypertension in the absence of any contraindication:
Thiazide diuretics: e.g. HCTZ, Chlorthalidone