Bronchodilators PG 874 Flashcards

1
Q

Beta2 Agonists Action

A

Stimulate the bronchial smooth muscle to dilate relaxing the brochioles. the stimulants and reuptake inhibitors increase levels of endogenous catecholamine.

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2
Q

what are Beta2 agonists used for

A

reversible airway obstruction caused by bronchospasm

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3
Q

What is an adverse effect caused from excessive use of the inhalant medication

A

paradoxical bronchospasm

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4
Q

What are some adverse effects of Beta2?

A

nausea, vomiting, restlessness, tachycardia and increased respirations, nervousness, headache, palpitations, and hyperglycemia

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5
Q

What are the 4 contraindications/warning/cautions of Beta2 agonist?

A

cardiac arrythmias, narrow angle glaucoma, beta blocker use (blocks all betas including beta2 which inhibits effects), caution for pts with diabetes mellitus (can increase serum blood glucose)

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6
Q

Muscarine Antagonist type and action

A

anticholinergic. antagonizes acetylcholine receptors producing bronchodilation

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7
Q

Use of muscarine antagonists (2)

A

symptomatic relief or prevention of bronchial asthma and management of COPD

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8
Q

Adverse effects of anticholinergics

A

drowsiness/sedation/flushed face, blurred vision/mydriasis, urinary retention, confusion/delirium, hallucinations, increased temp/HR, dry mouth

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9
Q

What are the contraindications/warning/caution of muscarinic antagonists

A

peptic ulcer, seizure, arrhythmias, hyperthyroid, older than 60, pregnancy class c (pros outweigh cons)

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10
Q

What does Leukotriene do?

A

Broncho constrictive substance released by the body during inflammation. Antagonist results in bronchodilation

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11
Q

What does a Mast Cell Stabilizer do?

A

Inhibit the release of substances that cause bronchoconstriction and inflammation from the mast cells in respiratory tract

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12
Q

What are the two uses for Leukotriene Antagonist and Mast Cell Stabilizers

A

Treatment of Asthma or COPD

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13
Q

What are the adverse effects of Leukotriene Antagonist and Mast Cell Stabilizers

A

Headache, dizziness, unpleasant taste, and fatigue

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14
Q

What are some contraindications/warnings/cautions for Leukotriene Antagonist and Mast Cell Stabilizers?

A

Acute asthma/bronchospasms, aspirin sensitive asthmatics

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15
Q

What action do inhaled corticosteroids have?

A

produce profound and varied metabolic effect, modify the normal immune response, and suppress inflammation

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16
Q

Why would you use an inhaled corticosteroid?

A

for their immunosuppressive, anti-inflammatory, or antineoplastic (Tx cancer). Help Tx asthma, chronic allergies, or inflammatory conditions.

17
Q

What are adverse effects of inhaled corticosteroids?

A

throat irritation, cough, candida albicans (yeast infection)

18
Q

What are contraindications/warnings/cation with inhaled corticosteroids?

A

acute bronchospasms, status asthmaticus, use caution with compromised immune systems