Naloxone & Ondansetron Flashcards

1
Q

Naloxone

Brand Name

A

Narcan

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2
Q

Naloxone

Class

A

Narcotic antagonist

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3
Q

Naloxone

Supply

A

prefilled syringe

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4
Q

Naloxone

Mechanism of Action

A

-acts as competitive antagonist at opiate receptors in the CNS
-reverses effects of narcotic and synthetic analgesic drugs: CNS depression, respiratory depression, respiratory arrest

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5
Q

Naloxone

Indications

A

-narcotic and synthetic analgesic drug overdose
(morphine, heroin, oxycodone, methadone, codeine, meperidine, fentanyl, hydrocodone, hydromorphone)
-unconsciousness of unknown etiology

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6
Q

Naloxone

Contraindication

A

-none in emergency setting

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7
Q

Naloxone

Adverse reactions

A

-withdrawal symptoms
such as:
-confusion
-hypotension
-tachycardia
-hypertension
-dysrhythmias
-diaphoresis
-nausea, vomiting

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8
Q

Naloxone

Routes

A

-IV
-IM
-IO
-ET
-IN

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9
Q

Naloxone

Onset

A

2-10 minutes

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10
Q

Naloxone

Adult Doses

A
  • 2.0mg, may repeat every 2 minutes
    -ET: 4.0mg diluted in 10mL NS
    -IN: 1.0mg sprayed in each nostril with MAD. may repeat every 2 minutes
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11
Q

Naloxone

Pediatric Doses

A
  • 0.1 mg/kg (max 2.0 mg per dose) may repeat every 2 minutes
    -ET: 2.0-4.0 mg diluted in 3-5mL NS
    -IN: 1.0mg sprayed in each nostril with MAD. may repeat every 2 minutes
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12
Q

Naloxone

Special Consideration

A

-duration is 20 minutes to 2 hours

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13
Q

Ondansetron

Brand Name

A

Zofran

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14
Q

Ondansetron

Class

A

Antiemetic

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15
Q

Ondansetron

Standard Supply

A
  • orally disintegrating tablet (ODT)
    -vial
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16
Q

Ondansetron

Mechanism of Action

A

-blocks serotonin 5-HT3 receptor sites in CNS
-inhibits nausea and vomiting

17
Q

Ondansetron

Indication

A

nausea and vomiting

18
Q

Ondansetron

Contraindication

A

known hypersensitivity

19
Q

Ondansetron

Adverse reactions

A

-headache
-dizziness

20
Q

Ondansetron

Routes

A

-oral
-IV
-IO

21
Q

Ondansetron

Onset

A

5-10 minutes

22
Q

Ondansetron

Adult Dose

A
  • Oral: 8.0 mg
  • IV/IO: 4.0-8.0 mg over 2-5 minutes
23
Q

Ondansetron

Pediatric Dose

A

4-14 years old: 4.0 mg
max dose 4.0 mg

24
Q

Ondansetron

Special Consideration

A

-peak effect is 2 hours
-duration of drug is 3-6 hours