Dopamine & Morphine Flashcards
Dopamine
Brand Name
Intropin
Dopamine
Class
-sympathomimetic
-vasopressor
Dopamine
Supply
premix bag
Dopamine
Mechanism of Action
-increases heart rate
-increases force of myocardial contractility
-increases blood pressure
-increases preload
Dopamine
Indications
-cardiogenic shock
-hemodynamically significant bradycardia
-hemodynamically significant hypotension
Dopamine
Contrindication
hemodynamically significant hypovolemic shock
Dopamine
Adverse Reactions
-extravasation may cause tissue necrosis
-increased myocardial oxygen demand
-tachycardia
-hypertension
-dysrhythmias
-dyspnea
-tremors
-palpitations
-headache
-nausea, vomiting
Dopamine
Route
infusion
Dopamine
Onset
1-4 minutes
Dopamine
Therapeutic Dosage Range & Responses
2.0-5.0 mcg/kg/minute
Negligible beta-adrenergic response
Dopamine
Therapeutic Dosage Range & Responses
5.0-10 mcg/kg/minute
Beta-adrenergic responses
-positive chronotropic effects
-positive inotropic effects
Dopamine
Therapeutic Dosage Range & Responses
10-20 mcg/kg/minute
Alpha-adrenergic responses
-vasoconstriction
-increased blood pressure
-increased preload
Dopamine
Therapeutic Dosage Range & Responses
>20 mcg/kg/minute
may increases heart rate and myocardial oxygen demand to undesirable limits
Dopamine
Adult Dose
2.0-20 mcg/kg/minute
Dopamine
Pediatric Dose
2.0-20 mcg/kg/minute
Dopamine
Special Consideration
infusion pump should be used when possible
Morphine
Class
-narcotic analgesic
-narcotic agonist
Morphine
Supply
-vial
-ampule
Morphine
Mechanism of Action
-alleviates pain by depressing CNS
-depresses brainstem respiratory centers
-decreases venous return to the heart
-decreases preload and afterload
Morphine
Indications
-moderate to severe pain
-chest pain and/or signs and symptoms suggestive of acute coronary syndrome
-acute cardiogenic pulmonary edema
Morphine
Contraindications
-known hypersensitivity
-head injury
-decreased level of consciousness
-hemodynamically significant hypotension
Morphine
Adverse Reactions
-CNS depression
-respiratory depression
-respiratory arrest
-hypotension
-bradycardia
-tachycardia
-dysrhythmias
-syncope
-dyspnea
-nausea, vomiting
Morphine
Routes
-IV
-IO
-IM
Morphine
Onset
immediate
Morphine
Adult Dose
1.0-4.0 mg increments over 1-5 minutes
Morphine
Pediatric Dose
0.1 - 0.2 mg/kg
Morphine
Special Considerations
-duration is 2-7 hours
-respiratory arrest/depression can be revered by naloxone
