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Drug Profiles > Ketamine & Midazolam > Flashcards

Ketamine & Midazolam Flashcards

1
Q

Ketamine

Brand

A

Ketalar

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2
Q

Ketamine

Class

A

-sedative
-anesthetic
-analgesic

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3
Q

Ketamine

Supply

A

Vial

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4
Q

Ketamine

Mechanism of action

A

-blocks pain receptors
-produces a dissociative state
-produces anesthesia

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5
Q

Ketamine

Indication

A

-procedural sedation for intubation

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6
Q

Ketamine

Contraindication

A

-known hypersensitivity
-not recommended for pediatrics

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7
Q

Ketamine

Adverse reactions

A

-respiratory depression
-respiratory arrest
-bradycardia
-tachycardia
-dysrhythmias
-hallucinations
-nausea, vomiting

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8
Q

Ketamine

Routes

A

-IV
-IO
-IM

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9
Q

Ketamine

Onset

A

30 seconds

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10
Q

Ketamine

Adult dose

A

-IV/IO: 1-2 mg/kg over 1 minute
-IM: 2-4 mg/kg

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11
Q

Ketamine

Special consideration

A

-duration is 5-10 mins

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12
Q

Midazolam

Brand

A

Versed

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13
Q

Midazolam

Class

A

-benzodiazepine
-anticonvulsant
-sedative
-hypnotic

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14
Q

Midazolam

Supply

A

Vial

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15
Q

Midazolam

Mechanism of action

A

-produces sedation by acting on limbic system, the thalamus, and hypothalamus
-binds to gamma-amino butyric acid (GABA) benzodiazepine receptors in the brain
-raises seizure threshold
-produces tranquillizing (anti anxiety) effect on CNS

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16
Q

Midazolam

Indications

A

-seizure activity
-status epilepticus
-procedural sedation for intubation and cardioversion
-chemical restraint for agitated (excited) delirium

17
Q

Midazolam

Contraindication

A

-known hypersensitivity

18
Q

Midazolam

Adverse reactions

A

-sedation
-transient amnesia
-respiratory depression/arrest
-bradycardia
-hypotension
-dizziness
-drowsiness
-blurred vision
-nausea, vomiting

19
Q

Midazolam

Route

A

-IV
-IO
-IM

20
Q

Midazolam

Onset

A

-IV/IO: 1-3 mins
-IM: 15 mins

21
Q

Midazolam

Adult dose for SEIZURES

A

-IV/IO: 0.1 mg/kg, max 4 mg
-IM: 0.2 mg/kg, max 10 mg

22
Q

Midazolam

Adult dose PROCEDURAL SEDATION IV/IO

A

0.5-2.5 mg, max 0.1 mg/kg

23
Q

Midazolam

Adult dose CHEMICAL RESTRAINT

A

-IV/IO: 0.05-0.1 mg/kg
-IM: 0.1-0.15 mg/kg

24
Q

Midazolam

Pediatric dose SEIZURES

A

-IV/IO: 0.05-0.1 mg/kg
-IM: 0.2 mg/kg, max 10mg

25
Q

Midazolam

Pediatric dose PROCEDURAL SEDATION IV/IO

A

0.05-0.5 mg/kg, max 0.1 mg/kg

26
Q

Midazolam

Special Considerations

A

-consider decreased dosages for elderly patients and patients with liver and kidney disease due to reduced metabolic function

Drug Profiles (16 decks)

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