Amiodarone & Atropine Flashcards
Amiodarone
Brand Name
Cordarone
Amiodarone
Class
Antidysrhythmic
Amiodarone
Supply
Prefilled syringe
Amiodarone
Mechanism of Action
-blocks sodium, potassium and calcium channels
-prolongs action potential and repolarization
-slows sinus rate
-increases PR interval and QT interval
Amiodarone
Indications
-VFib
-pulseless VTach
-wide complex tachycardia
Amiodarone
Contraindications
-cardiogenic shock
-hemodynamically significant bradycardia
-second degree and third degree heart block
-hemodynamically significant hypotension
Amiodarone
Adverse Reactions
-bradycardia
-hypotension
-heart block
-congestive heart failure
-headache
-dizziness
-nausea, vomiting
Amiodarone
Routes
-IV
-IO
-infusion
Amiodarone
Onset
1-3 minutes
Amiodarone
Adult Dose
Cardiac Arrest
300 mg
if no response, administer 150 mg over 3-5 mins
Amiodarone
Adult Dose
Tachydysrhythmias
150 mg in 50 mL D5W over 10 minutes
Amiodarone
Adult Dose
Infusion
1.0 mg/minute
Amiodarone
Pediatric Dose
VFib
5.0 mg/kg. max dose 300 mg.
may repeat dose every 5 mins twice
Amiodarone
Pediatric Dose
VTach
5.0 mg/kg over 20 minutes
may repeat dose twice
Amiodarone
Special Consideration
monitoring of cardiac rhythm for prolonged PR interval and QT interval is required during administration of drug
Atropine Sulfate
Classes
-anticholinergic
-parasympathetic blocker
-antidote
Atropine Sulfate
Supply
-prefilled syringe
-vial
Atropine Sulfate
Mechanism of Action
-blocks action of acetylcholine
-increases heart rate
-reverses symptoms of cholinergic poisoning
Atropine Sulfate
Indications
-hemodynamically significant bradycardia
-organophosphate poisoning
-carbamate poisoning
-nerve agent exposure
Atropine Sulfate
Contraindications
-known hypersensitivity
-tachycardia
-hypothermic hemodynamically significant bradycardia
Atropine Sulfate
Adverse Reactions
-tachycardia
-palpitations
-flushed, hot, dry skin
-dizziness
-drowsiness
-confusion
-anxiety
-headache
-dilated pupils
-blurred vision
-dry mouth
-nausea, vomiting
Atropine Sulfate
Routes
-IV
-IO
-ET
Atropine Sulfate
Onset
Immediate
Atropine Sulfate
Adult Dose
Hemodynamically significant bradycardia
0.5mg
may repeat every 3-5 mins to max dose of 3.0 mg
Atropine Sulfate
Adult Dose
Organophosphate poisoning/carbamate poisoning/nerve agent exposure
1.0-4.0 mg
may double dose every 5 minutes
Atropine Sulfate
Adult Dose
ET
2.0-2.5 mg diluted in 10 mL NS
Atropine Sulfate
Pediatric Dose
Hemodynamically significant bradycardia
0.02 mg/kg
may repeat dose every 3-5 mins to max dose 1.0 mg in children and 2.0 mg in adolescents
Atropine Sulfate
Pediatric Dose
Organophosphate poisoning/carbamate poisoning/nerve agent exposure
0.03 - 0.05 mg/kg every 10-20 mins
Atropine Sulfate
Special Consideration
consider transcutaneous pacing for refractory bradydysrhythmias
