Amiodarone & Atropine

Question 1

Amiodarone

Brand Name

Answer 1

Cordarone

Question 2

Amiodarone

Class

Answer 2

Antidysrhythmic

Question 3

Amiodarone

Supply

Answer 3

Prefilled syringe

Question 4

Amiodarone

Mechanism of Action

Answer 4

-blocks sodium, potassium and calcium channels
-prolongs action potential and repolarization
-slows sinus rate
-increases PR interval and QT interval

Question 5

Amiodarone

Indications

Answer 5

-VFib
-pulseless VTach
-wide complex tachycardia

Question 6

Amiodarone

Contraindications

Answer 6

-cardiogenic shock
-hemodynamically significant bradycardia
-second degree and third degree heart block
-hemodynamically significant hypotension

Question 7

Amiodarone

Adverse Reactions

Answer 7

-bradycardia
-hypotension
-heart block
-congestive heart failure
-headache
-dizziness
-nausea, vomiting

Question 8

Amiodarone

Routes

Answer 8

-IV
-IO
-infusion

Question 9

Amiodarone

Onset

Answer 9

1-3 minutes

Question 10

Amiodarone

Adult Dose
Cardiac Arrest

Answer 10

300 mg
if no response, administer 150 mg over 3-5 mins

Question 11

Amiodarone

Adult Dose
Tachydysrhythmias

Answer 11

150 mg in 50 mL D5W over 10 minutes

Question 12

Amiodarone

Adult Dose
Infusion

Answer 12

1.0 mg/minute

Question 13

Amiodarone

Pediatric Dose
VFib

Answer 13

5.0 mg/kg. max dose 300 mg.
may repeat dose every 5 mins twice

Question 14

Amiodarone

Pediatric Dose
VTach

Answer 14

5.0 mg/kg over 20 minutes
may repeat dose twice

Question 15

Amiodarone

Special Consideration

Answer 15

monitoring of cardiac rhythm for prolonged PR interval and QT interval is required during administration of drug

Question 16

Atropine Sulfate

Classes

Answer 16

-anticholinergic
-parasympathetic blocker
-antidote

Question 17

Atropine Sulfate

Supply

Answer 17

-prefilled syringe
-vial

Question 18

Atropine Sulfate

Mechanism of Action

Answer 18

-blocks action of acetylcholine
-increases heart rate
-reverses symptoms of cholinergic poisoning

Question 19

Atropine Sulfate

Indications

Answer 19

-hemodynamically significant bradycardia
-organophosphate poisoning
-carbamate poisoning
-nerve agent exposure

Question 20

Atropine Sulfate

Contraindications

Answer 20

-known hypersensitivity
-tachycardia
-hypothermic hemodynamically significant bradycardia

Question 21

Atropine Sulfate

Adverse Reactions

Answer 21

-tachycardia
-palpitations
-flushed, hot, dry skin
-dizziness
-drowsiness
-confusion
-anxiety
-headache
-dilated pupils
-blurred vision
-dry mouth
-nausea, vomiting

Question 22

Atropine Sulfate

Routes

Answer 22

-IV
-IO
-ET

Question 23

Atropine Sulfate

Onset

Answer 23

Immediate

Question 24

Atropine Sulfate

Adult Dose
Hemodynamically significant bradycardia

Answer 24

0.5mg
may repeat every 3-5 mins to max dose of 3.0 mg

Question 25

Atropine Sulfate

Adult Dose
Organophosphate poisoning/carbamate poisoning/nerve agent exposure

Answer 25

1.0-4.0 mg
may double dose every 5 minutes

Question 26

Atropine Sulfate

Adult Dose
ET

Answer 26

2.0-2.5 mg diluted in 10 mL NS

Question 27

Atropine Sulfate

Pediatric Dose
Hemodynamically significant bradycardia

Answer 27

0.02 mg/kg
may repeat dose every 3-5 mins to max dose 1.0 mg in children and 2.0 mg in adolescents

Question 28

Atropine Sulfate

Pediatric Dose
Organophosphate poisoning/carbamate poisoning/nerve agent exposure

Answer 28

0.03 - 0.05 mg/kg every 10-20 mins

Question 29

Atropine Sulfate

Special Consideration

Answer 29

consider transcutaneous pacing for refractory bradydysrhythmias