Naloxone (Narcan)

Question 1

Naloxone Class?

Answer 1

Opioid antagonist

Question 2

Naloxone Action?

Answer 2

Narcan is a competitive opiate antagonist used in known or suspected opioid overdose.

Question 3

Naloxone Indications?

Answer 3

Suspected or known opioid overdose with respiratory depression.

Question 4

Naloxone Contraindications?

Answer 4

: Hypersensitivity. Caution with narcotic dependent pt’s who may experience
withdrawal syndrome to include neonates of narcotic-dependent mothers. Avoid use with
Meperidine induced seizures.

Question 5

Naloxone Onset/Duration?

Answer 5

Onset: 2 min
Duration: 30-120 min

Question 6

Naloxone Dose/Route?

Answer 6

Adult: 0.4 – 2mg IV/IO/IM/IN may repeat up to 10 mg max

Peds: 0.1 mg/kg IV/IO/IM/IN, max single dose of 2 mg

Question 7

Naloxone Side Effects?

Answer 7

Withdrawal symptoms, dysrhythmias, nausea/vomiting, hypertension,
tachycardia, seizures, blurred vision.

Question 8

Naloxone Notes*

Answer 8

Titrate to control airway and breathing, should NOT be used to completely reverse
narcotic effects due to complications with withdrawal syndrome, combativeness, etc.