Diazepam (Valium)

Question 1

Diazepam Class?

Answer 1

Benzodiazepine

Question 2

Diazepam Action?

Answer 2

Increases the activity of the inhibitory neurotransmitter GABA, thereby producing a sedative effect, relaxing skeletal muscles, and raising the seizure threshold

Question 3

Diazepam Indications?

Answer 3

Seizure activity, acute anxiety, skeletal muscle relaxation, sedation for pacing, acute alcohol withdrawal

Question 4

Diazepam Contraindications?

Answer 4

Hypersensitivity, respiratory depression, head injury with CNS depression, shock, coma

Question 5

Diazepam Onset/Duration?

Answer 5

Onset : 1-5 min IV and 15-30 min IM

Duration : 15-60 min IV and 15 - 60 min IM

Question 6

Diazepam Dose/Route?

Answer 6

Adult : Seizures - 5 to 10mg IV over 2 minutes every 10-15 mins as needed and a max of 30mg.
Premedication for pacing - 5 to 15mg IV

Peds : Ages 30 days to 5 yrs - 0.2 to 0.5mg slow IV push over 2 minutes every 2-5 mins to a max of 5mg.
Ages 5 yrs or older - 1mg slow IV push over 2 mins every 2-5 mins with a max of 10mg.

Question 7

Diazepam Side Effects?

Answer 7

Respiratory depression, altered LOC, hypotension, amnesia, confusion, nausea, vomiting, blurred vision