Morphine Sulfate

Question 1

Morphine Class?

Answer 1

Opioid analgesic

Question 2

Morphine Action?

Answer 2

Morphine is a natural opioid analgesic. Morphine also causes venous dilation and decreased venous return to the heart thus reducing myocardial oxygen demand. Morphine also causes euphoria, central nervous system depression and sedation.

Question 3

Morphine Indications?

Answer 3

Acute pain, chest pain associated with ACS, pulmonary edema

Question 4

Morphine Contraindications?

Answer 4

Hypersensitivity to narcotics, CNS depression, respiratory depression, hypotension, hypovolemia, head injury, increased ICP, respiratory depression, pts that took MAO inhibitors in last 14 days, and caution with pt’s with RV infraction/MI

Question 5

Morphine Onset/Duration?

Answer 5

Onset: 5-10 min
Duration: 4-5 hrs

Question 6

Morphine Dose/Route?

Answer 6

Adult: 2-5 mg IV repeat every 10 min as needed

Peds: 0.1 mg/kg IV, every 10 min up to 5 mg max single dose, max total dose of 15 mg

Question 7

Morphine Side Effects?

Answer 7

Hypotension, CNS depression, tachycardia, respiratory depression

Question 8

Morphine Note*

Answer 8

CNS depressants and Phenothiazines may potentiate morphine. Use Narcan for Morphine overdoses.