Midazolam (Versed)

Question 1

Midazolam Class?

Answer 1

Benzodiazepine

Question 2

Midazolam Action?

Answer 2

Increases the activity of the inhibitory neurotransmitter GABA, thereby producing a sedative effect, relaxing skeletal muscles, and raising the seizure threshold.

Question 3

Midazolam Indications?

Answer 3

Seizures and anxiety. Premedication for intubation, cardioversion or conscious sedation procedures.

Question 4

Midazolam Contraindications?

Answer 4

Hypersensitivity, shock, respiratory depression, depressed VS. Use caution with CNS depressants including barbiturates, alcohol, and narcotics and glaucoma.

Question 5

Midazolam Onset/Duration?

Answer 5

Onset: 1-3 min IV
Duration: 2-6 hours IV

Question 6

Midazolam Dose/Route?

Answer 6

Adult: 2-5 mg IV/IO/IM/IN, every 5 min up to 10 mg max total dose.

Peds: 0.2 mg/kg IV/IO/IM/IN, every 5 min up to 5 mg max single dose.

Question 7

Midazolam Side Effects?

Answer 7

Hypotension, respiratory depression or arrest, CNS depression, hiccups, oversedation, blurred vision.

Question 8

Midazolam Note*

Answer 8

May be given IM since Midazolam is water based. Should be given with analgesic for painful procedures.