Muscular System Flashcards

1
Q

Properties of Skeletal muscle

A

Support & movement, blood propulsion, thermoregulation, striated
• Voluntary (somatic) control
• Multinucelated

Can be red or white fibers

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2
Q

Skeletal muscle red fibers

A

Slow twitch. Support (dark meat). Carry out oxidative

phosphorylation.

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3
Q

White Fibers:

Skeletal muscle

A

Fast-twitch. Active (white meat). Anaerobic metabolism.

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4
Q

Properties of smooth muscle, where is it found?

A

Respiratory, reproductive, cardiovascular, digestive
• Involuntary (autonomic) control
• Uninucleated
• Can display myogenic activity without neural input

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5
Q

Properties of cardiac muscle?

A
Contractile tissue of the heart
• Involuntary (autonomic) control
• Uninucleated (sometimes binucleated)
• Can display myogenic activity
• Cells connected with intercalated discs that contain gap junctions
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6
Q

Which germ layer is the skeletal system dervived from?

A

Mesoderm

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7
Q

Axial Skeleton

A

Skull, vertebral column, ribcage, hyoid bone

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8
Q

Appendicular Skeleton

A

Bones of limbs, pectoral girdle, pelvis.

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9
Q

Bones of limbs, pectoral girdle, pelvis.

A

Lattice-like structure of bony spicules known as trabeculae.
Cavities filled with bone marrow

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10
Q

Red bone marrow

A

Filled with hematopoietic stem cells

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11
Q

yellow bone marrow

A

Yellow: fat

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12
Q

Long Bones

A

Shafts called diaphysis that flare to form metaphyses and
that terminate in epiphyses. Epiphyses contain
epiphyseal (growth) plate.

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13
Q

Periosteum:

A

Connective tissue that surrounds bone.

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14
Q

Ligaments:

A

Attach bones to other bones

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15
Q

Tendons

A

: Attach bones to muscles.

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16
Q

Bone Matrix: Osteons

A

Osteons are the chief structural unit of compact bone,
consisting of concentric bone layers called lamellae, which
surround a long hollow passageway, the Haversian canal.
Between rings are lacunae, where osteocytes reside,
which are connected with cancaliculi.

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17
Q

Osteoblasts

A

build bone

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18
Q

Osteoclasts

A

Reabsorb bone

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19
Q

What does parathyroid hormone release do to bone reabsorption and calcium levels?

A

Increases reabsorption of bone and increases blood calcium

20
Q

What effect does vitamin D have on bone reabsorption and blood calcium

A

Increase both

21
Q

What effect does calcitonin have on bone formation and calcium in the blood

A

Increases bone formation and decreases blood calcium concentration

22
Q

What secretes cartilage?

A

Chondrocytes

23
Q

Is cartilage innervated?

24
Q

Immovable joints

A

Fused together to form sutures

25
Movable joints
Strengthened by ligaments and contain a synovial capsule
26
Synovial fluid
Secreted by synovium and it lubricates joints
27
Fetal bones
Bones form from cartilage through endochondroal ossification. Skull bones form directly from mesenchyme in intramembranous ossification.
28
Sacromeres
Basic contractile unit of striated muscle
29
Are myosin thick or thin?
Thick
30
Are actin thick or think filaments?
Thin
31
Where are troponin and tropomyosin found and what do they do?
Troponin & tropomyosin found on the thin filament and regulate actinmyosin interactions
32
Z-lines:
Define the boundary of each sarcomere
33
M-line
Middle of sarcomere
34
o I-band:
Only actin filaments.
35
H-zone:
Only myosin filaments.
36
A-band
Contains both actin and myosin. Only part that | maintains a constant size during contraction.
37
What happens to the z lines and the I bands as the sarcomere contracts?
Gets closer together
38
What happens to the A band when the sarcomere contracts?
Stays the same
39
Sarcoplasmic Reticulum:
Ca2+ filled modified endoplasmic reticulum.
40
Sarcolemma:
Cell membrane of a myocyte
41
T-tubules:
Connected to sarcolemma. Carry signals
42
Describe the process of contraction and relaxation
Begins at neuromuscular junction, where the efferent neuron release acetylcholine that binds to receptors on the sarcolemma, causing depolarization • Depolarization spreads down sarcolemma to T-tubules, triggering the release of Ca2+ • Ca2+ binds to troponin, causing a shift in tropomyosin and exposure of the myosin-binding sites on the actin filament • Shortening of the sarcomere occurs as myosin heads bind to the exposed sites on actin, forming cross bridges and pulling the actin filament along the thick filament. “Sliding filament model” • Muscles relax when acetylcholine is degraded by acetylcholinesterase, terminating the signal and allowing Ca2+ to return to the SR. • ATP binds to myosin head, allowing it to release form actin
43
Simple Twitch:
: Single muscle fiber responds to brief stimulus.
44
Frequency Summation:
Addition of multiple simple twitches before the | muscle has a chance to fully relax.
45
Oxygen Debt:
Difference between O2 needed and O2 present.
46
Creatine Phosphate:
Adds a phosphate group to ADP, forming ATP
47
Myoglobin:
Heme-containing protein that is a muscular | oxygen reserve.