Growth Signals Flashcards

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1
Q

Positive Growth Signals

A

1) CDK + Cyclin create a complex
2) Phosphorylate Rb to Rb + P
3) Rb changes shape, releases E2F
4) Cell division continues

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2
Q

Negative Growth Signals:

A

1) CDK inhibitors block phosphorylation of Rb
2) So, E2F stays attached
3) Cell cycle halts

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