muscle physiology Flashcards
3 muscle types
skeletal, cardiac, smooth
skeletal muscle
most abundant type (700+), functions: movement of skeleton, posture, supports soft tissue, guards entrances and exits, maintains body temp
myofibril
protein bundle inside of a muscle cell
muscle fiber
one cell
fascicle
bundle of cells
a bunch of fascicles
skeletal muscle (organ)
tendons
attach muscle to bone
length of skeletal muscle cell
can be up to 24 inches
sarcomere
1 functioning unit of muscle cell
myosin
thick filaments in sarcomere
has head and tail
many myosin proteins make up thick filament
actin
thin filaments in sarcomere
z line
boundary of sarcomere
A band
area where thick filaments exist
I band
area where thin filaments exist
m line
center of sarcomere
striations are the result of
actin and myosin
muscle contractions are the result of
interactions between actin and myosin
tropomyosin
fibrous protein that wraps helically around actin
troponin
calcium binding sites found on tropomyosin
contraction
thousands of myosin heads creating power strokes (see book for steps)
rigor mortis
at death, run out of ATP. Ca leaks out of the sarcoplasmic reticulum and cross bridges form. without ATP the cross bridge can’t be broken. 15-25 hours later enzymes from lysosomes break myofilaments down
tetanus
caused by Clostridium tetani, bacteria releases toxin that causes constant state of contraction. 40-60% mortality rate. aka lock jaw
muscle tone
sarcomere is active during rest. no muscle contraction. stabilizes joints for posture and balance. varies per individual
atrophy
muscles not stimulated on regular basis causes smaller and weaker cells (like from being in a cast)