Muscle Contraction Flashcards
mechanism of muscle contraction structure of skeletal muscles
✓ muscle
✓ muscle fascicle
✓ muscle fiber
✓ myofibrils
myofibrils contractile elements, what element?
actin and myosin
Muscle fiber
- Sarcolemma
- Sarcoplasm
- Myofibrils
Actin Filaments
a. F actin strands
b. tropomyosin
c. troponin (T, I, C)
during contraction
✓ I- band disappear
✓ H- band disappear
✓ M- band disappear
✓ the length of sarcomere decreases
Mechanism of Muscle Contraction (Steps)
✓ Step 1. nerve impulses travel toward the synaptic knob
✓ Step 2. Ca ++ ion from the ECF inter into the synaptic knob through the calcium channel
✓ Step 3. As Ca ++ enters the synaptic knob, acetylcholine vesicles rupture and is released out into the synaptic cleft by exocytosis
✓ Step 4. Ach diffuses across the neuromuscular junctions and binds to the receptor sites on the postsynaptic membrane.
✓ Step 5. Stimulating the receptor causes a conformational change in the postsynaptic membrane and generates an action potential.
✓ Step 6. this action potential travels through along the length of muscle fiber, and the penetrates deep into the muscle through the T-tubular system
✓ Step 7. The electric impulse stimulates the sarcoplasmic reticulum to release calcium
✓ Step 8. Calcium bind with troponin- C and activates myosin ATPase