Mucous Membrane Disorders Flashcards

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1
Q

Cheilitis common in

A

AIDS

SE of PI

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2
Q

ACD of lip

A

Vermillion MC
f>M
Fragrance and nickel MC

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3
Q

Angular cheilitis

A

Elderly who wear dentures

Decreased vertical dimension of face

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4
Q

Plasma cell cheilitis

A

Sharply defined, dark red infiltrated plaque with a lacquer like glaze
Reactive

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5
Q

Plasmacanthoma

A

Verrucous tumor along the angles
Spectrum with plasma cell cheilitis
C albicans found
May involve perianal, periumbilical, inguinal, and toe webs

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6
Q

Drug induced ulcer of the lip

A

Painful, well defined ulceration of lower lip that heals with Med withdrawal
Phenylbutazone, chlorpromazine, phenobarbital, methyldopa, thiazides diuretics

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7
Q

Oral crohns

A

Metallic dysgeusia, gingival bleeding, diffuse oral swelling, focal mucosal hypertrophy and fissuring (cobblestoning), ulceration, polyploid lesions, indurated lower lip fissure, angular cheilitis, gran cheilitis, pyo veg

Oral involvement in 10-20% of crohns, esp males with early onset dz

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8
Q

Cutaneous findings in crohns

A

PG (more UC), EN, polyarteritis nodosa, pellagra, pernicious anemia, acrodrmatitis like rxn, urticaria, necrotizing vasculitis

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9
Q

Pyostomatitis vegetans

A

UC > crohns
Sclerosing cholangitis
Dense aggregates of neuts and eos
May see annular plaques of axilla, groin, scalp (pyodermatitis vegetans)

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10
Q

Melkerson rosenthal associations

A

Mega colon, otosclerosis, craniopharyngioma, odontogenic infection
Neuropathic origin?

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11
Q

Nicotine stomatitis

A

Hot beverages, heavy smokers, most severe with pipes

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12
Q

Fissured tongue (lingua plicata)

A

MRos, downs, PC, pemphigus vegetans, cowden

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13
Q

Geographic tongue

A

MC isolated
May be a manifestation of atopy or PSO, AIDS, lithium
Red patches with a white border, serpiginous
No sx, occasional glossodynia
No tx or retin a solution

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14
Q

Black hairy tongue

A

Benign hyperplasia of filliform papilla

Smoking, ab, psychotropic meds, candida

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15
Q

Hunter or moeller glossitis

A

Smooth tongue with b12 def

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16
Q

Eruptive lingual papillitis

A

Mean age 3, seasonal
Difficulty eating, fever, intense salivation
Hypertrophic of fungiform papillae
Involution in 2-15 days, avg week

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17
Q

Eosinophilic ulcer of the oral mucosa

A
Ulcer with indurated and elevated border with pseudomembrane
Posterior tongue
Post traumatic
Self limited
Cd30 cells in recurrent multifocal cases
18
Q

Caviar tongue

A

Elastic degeneration

Phleboliths and thrombophlebitis may complicate

19
Q

Epdermization of the lip

A

Smooth leukokeratosis of lower lip

20
Q

Proliferative verrucous leukoplakia

A

F MC
70% become SCC (palate and gingiva especially)
Some associated with HPV 16, SCC RF not present

21
Q

Acquired dyskeratotic leukoplakia

A

White plaques of gingiva, lips, palate

Unique finding of dyskeratotic cells of prickle layer

22
Q

White sponge nevus

A
Acanthosis, vacuolated prickle cells, acidophilus condensations in cyto of keratinocytes (aggregated tonofilaments)
Buccal mucosa MC, no extramucosal
Progression stops at puberty
Hpv16 found in some
Tx = TCN
23
Q

Ephelides

A

Lower lip
Darken with sun

Oral melanotic macules - young women, don’t darken with sun, acanthosis and basilar melanin on bx

Melanoacanthoma - proliferation of keratinocytes and melanocytes, young black pts on buccal mucosa, reactive, 40% spont resolve

24
Q

Oral melanoma

A

Palate MC

Less than 5% survival at 5 yrs

25
Q

Oral pigmentation

A

Amiodaquine, chloraquine, OCP, phenothiazines, quinacrine, quinidine, thallium, azt

26
Q

Osseous choristoma of tongue

A

Nodule on dorsal tongue containing mature lamellar bone

27
Q

Peripheral ameloblastoma

A

Gingiva of lower jaw in M in his 50s
Growing pink sessile mass
19% recurrence after excision
BCC simulated histologically

28
Q

Trumpeters wart

A

Firm hyperkeratosis nodule on upper lip of trumpet player

29
Q

Epulis

A

Benign lesion of gingiva, reactive

Giant cell epulis bluish red on gingiva, induced by dental implants, Cherubism, resemble GCT of the tendon sheath

30
Q

Oral PG

A

MC gingiva

31
Q

Granuloma fissuratum

A

Circumscribed, firm, whitish on the labioalveolar fold

Chronic irritation like poorly fitting dentures

32
Q

Angina bullosa haemorrhagica

A

Sudden blood blisters on oral mucosa
No associated dz
May be recurrent

33
Q

Multiple mucoceles

A

GVHD
Rupture of salivary glands with extravasated of sialomucin

Parotid duct cyst- musicians who play wind instruments, opposite the upper 2nd molar on buccal mucosa

Dermoid cyst - may occur on mouth floor

34
Q

Trench mouth RF

A

Poor dental hygiene and nutrition, smoking, ectasy, immunosuppressive

Noma- fusospirillary gangrenous stomatitis in kids, triggered by measles

35
Q

Acatalasemia (takaharas dz)

A

Catalase def in liver, m., BM, rbcs and skin
Progressive mouth gangrene
H202 added to blood turns blackish brown and doesn’t foam
Tx is extraction of diseased teeth and ab

36
Q

PFAPA

A

Tonsillectomy cures

37
Q

Oral hsv

A

Affects keratinzed mucosa of palate, gingiva, tongue that’s is attached to bone (herpangina and aphthous ulcers affect nonattached mucosa)

38
Q

Aphthous stomatitis

A

White with a ring of hyperemia
Buccal or labial mucosa > edge of tongue> soft palate
Affect nonkeratinized mucosa not attached to bone
Rarely confluent (vs herpes)
MC lesion of oral mucosa
Maslow 5 min before meals held in mouth, kaolin can be added
Fluocinonide in orabase
Colchicine, dapsone

39
Q

Major aphthous ulcer (Suttons dz)

A

HIV associated

40
Q

Behcets

A

Dirty gray base with a bright red halo
Ocular lesions start with periorbital pain and photophobia, may see conjunctivitis and hypopyon, both eyes eventually involved
CNS resemble MS
Thrombophlebitis, thrombosis of the superior vena cava
Polyarthritis MC
LCV or neutrophilic vascular rxn on path
Sucralafate- colchicine- dapsone-thalidomide-mtx