Dermatoses From Physical Factors Flashcards
First degree burn
Congestion of superficial blood vessels
Superficial 2nd degree burn
Transudation of serum from capillaries -> edema
Deep 2nd degree burn
Pale and anesthetic
To reticular dermis
3rd degree burn
Appendages destroyed
What facilitates the removal of hot tar burns
Polyoxyethylene sorbitan or sunflower oil
Drugs that induce milia crystallina
Isotretinoin, doxorubicin, bethanechol
What layer is the injury to in miliaria rubria
Prickle layer = SS
“Prickly heat”
Miliaria pustulosa
Typically preceded by another dermatosis that blocks sweat ducts
Intertriginous, back of bedridden pts
Pustules Independent of hair follicles
Recurrent episodes in type 1 pseudohypoaldosteronism
Level of occlusion is miliaria profunda
Upper dermis
Usually lasts only an hour
Acrocyanosis but not raynauds
No ulceration
Not temporary
May induce acrocyanosis of nose, ears, dorsal hands
Inhaled butyl nitrite
- AC also induced by IFN alpha
- may be seen in anorexia
Puffy hand syndrome
Lymphedema due toe injection of narcotics to dorsal hand
Pernod may be presenting sign
Leukemia cutis
Treatment of frostbite
Rapid rewarming btw 37 and 43 degrees c
- tpa may reduce amputation
- arthritis may be a late complication
UV and clothing
Baggy clothes, clothes that have been washed more are more effective filters
*Tinosorb containing material for laundering = sunguard
Yellowish papules along the sides of the neck from sebaceous hyperplasia from sun damage
Fibroelastolytic papules of the neck
Pearly papule on the face or chest from elastosis
Dubreuilh elastoma
Effects of UV
Induce ROS through AP-1
Increases transcription of MMP 1 (collagenase) MMP 3 (stromoelysin 1), and MMP9 (gelatinase) to form collagen fragments
Increased deposition of fibulin 2
Decreased types 1&3 collagen
Adult colloid millium derived from
Elastic fibers
- associated with petrochemical exposure
Juvenile colloid milium
Apoptotic keratinocytes
Action spectra for photo allergy
320-425
% of pmle patients with a positive ANA
10-20%
PMLE action spectra
UVA (MC)»_space; UVB or A+B»_space; visible light
- women more commonly sensitive to UVA alone, men more commonly to visible lt
Actinic prurigo
May occur in sun protected sites like buttocks
60% resolve in 5 yrs in children, adults more persistent
Hardening does NOT occur
Solar urticaria
UVA
Drugs associated with solar urticaria
TCN (but not mino)
Chlorpromazine
Progesteronal agents
Repirinast
SU associations
PCT, EPP, SLE
Hydroa vacciniforme action spectra
UVA (330-360)
What % of hiv pts have photosensitivity
5%, typically cd4<200
Chronic actinic derm action spectra
UVA + UVB + visible MC > UVA + UVB > A or B
Eosinophilic polymorphic and pruritic eruption associated with radiotherapy
Days to mo after
Not limited to radiation sites
MC cancer after radiotherapy
BCC
*scc more common on dorsal hands
MC site for pressure ulcer
Pelvic area
Fracture blisters
Occur due to vascular compromise
Days to 3 weeks after
Esp lower leg
Photosensitive tattoo pigment
Cadmium = yellow
DLE has been reported in what color tattoos
Red
Pseudolymphoma tattoo reaction
Red
Granulomas
Silicone, mercury (sarciodal, positive gold lysis test), zirconium (a Lila, sarcoidal), silica (associated with systemic sarcoid)
