MT6312 LEC UNIT 4 Flashcards
Also known as chronic diseases
Communicable disease
Non-communicable diseases are of_____ duration and generally _____ progression
long
slow
Non-communicable diseases are a result from combinations of _____,______,_____ and _____ factors
genetic, physiological,
environmental and behaviors
Characteristics of Non-communicable disease
- Complex etiology (causes)
- Multiple risk factors
- Long latency period
- Non-contagious origin
- Prolonged course of illness
- Functional impairment or disability
- Incurability
- Insidious onset
characteristic, condition, or behaviour that increases the likelihood of getting a disease or injury
Risk factor
Risk factors can either be ____ or _____
modifiable or nonmodifiable.
Surveillance of non-communicable can be difficult because of?
- Lag time between exposure and health condition,
- More than one exposure for a health condition, and
- Exposure link to more than one health condition .
_______ are needed to prevent disease.
Intervention that target risk factors
Risk factor surveillance cycle
Change people’s behavior
Reduce risk
Reduce burden of disease
A risk factor that cannot be reduced or controlled by intervention
Non-Modifiable Risk Factors
Examples of Non-Modifiable Risk Factors
- Age
- Gender
- Race, and
- Family history (genetics)
A behavioral risk factor that can be reduced or controlled by intervention, thereby reducing the probability of disease.
Modifiable Risk Factors
WHO has prioritized the following FOUR Modifiable Risk Factors, which are?
- Physical Inactivity
- Tobacco use
- Alcohol use, and
- Unhealthy diets
Tobacco kills up to how much of its users?
Half
Annual death toll of tobacco can rise up to ____ by 2030
8million
Nearly 80% of the world’s 1 billion smokers live in ______ and ______ – income countries.
low – and in middle
Among smokers, what are some sicknesses that could develop?
Cancer
Coronary heart disease
Lung disease
Peripheral vascular disease
Stroke
Fetal complications and stillbirth
Most countries have increased overall daily consumption of?
- Daily calories,
- Fats and meats and
- Energy dense and nutrient- poor foods such as:
- starches
- refined sugars
- trans-fats
Unhealthy Diet: Health Effects
Coronary heart disease
Stroke
Cancer
Type 2 Diabetes
Hypertension
Liver and gallbladder disease
Obesity
____ of the world’s population does not get enough physical activity.
31%
Many social and economic changes contribute to physical inactivity, which are?
- Aging populations
- Transportation, and
- Communication technology
____ of major NCDs worldwide is attributable to physical inactivity
6-10%
____ of all global drinkers are episodic, heavy drinkers.
11.5%
_____ people die from alcohol consumption per year.
2.5 million
Refers to the biochemical processes involved in the body’s normal functioning.
Metabolic
_____ can lead to metabolic/physiologic changes.
Behaviors (modifiable risk factors)
WHO has prioritized the following four metabolic risk factors, which are?
- Raised blood pressure
- Raised total cholesterol
- Elevated glucose
- Overweight and Obesity
TOP 3 Leading Non-Communicable Diseases (Mortality rates) in the Philippines, both sexes, all ages in 2017 is?
Cardiovascular disease
Neoplasms
Diabetes and CKD
Group of disorders of the heart and blood vessels
CARDIOVASCULAR DISEASES
The number 1 cause of death globally, taking an estimated 17.9 million lives each year
CARDIOVASCULAR DISEASES
Symptoms of CARDIOVASCULAR DISEASES
- Heart attack
- Arrythmia
- Heart failure
disease of the blood vessels supplying the heart muscle
Coronary Heart Disease
disease of the blood vessels supplying the brain
Cerebrovascular Disease
disease of blood vessels supplying the arms and legs
Peripheral Arterial Disease
damage to the heart muscle and heart valves caused by streptococcal bacteria
Rheumatic Heart Disease
malformations of heart structure existing at birth
Congenital Heart Disease
blood clots in the leg veins, which can dislodge and move to the heart and lungs
Deep Vein Thrombosis And Pulmonary Embolism
Major Modifiable Risk Factors for Cardiovascular disease
- High BP
- Abnormal blood lipids
- Tobacco use
- Physical inactivity
- Obesity
- Unhealthy diet (salt)
- Diabetes
Other modifiable RFs for Cardiovascular disease
- Low socio-economic status
- Mental ill-health (depression)
- Psychosocial stress
- Heavy alcohol use
- Use of certain medication
- Lipoprotein
“Novel” Risk Factors for Cardiovascular disease
- Excess homocysteine in blood
- Inflammatory markers (C-reactive protein)
- Abnormal blood coagulation (elevated blood levels of fibrinogen)
A chronic disease that occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces leading to hyperglycemia
DIABETES MELLITUS
DM may lead to serious damage to many of the body’s systems, especially the _____ and ______
nerves and blood vessels
Diabetes prevalence has been rising more rapidly in ____ and ______ income countries
middle- and low-
The number of people with diabetes has risen from ____ in 1980 to _____ in 2014
108 million
422 million
An estimated _____ deaths were directly caused by diabetes
1.5 million
previously known as insulin-dependent, juvenile or childhood-onset
DM 1
T or F: DM1 is of unknown cause and not preventable with current knowledge
T
characterized by deficient insulin production and requires daily administration of insulin
DM1
DM 2 previously known as?
non-insulin-dependent, or adult-onset
Why was DM2 formerly called non-insulin-dependent, or adult-onset?
Due to the body’s ineffective use of insulin
DM2 is a result of?
Result of excess body weight and physical inactivity
a temporary condition that occurs in pregnancy and carries long-term risk of type 2 diabetes
Gestational Diabetes Mellitus
Characteristic glucose levels in gestational DM?
hyperglycaemia with blood glucose values above normal but below those diagnostic of diabetes
How id gestational DM diagnosed?
prenatal screening, rather than through reported symptoms
Signs and Symptoms of DM
- Polyuria
- Polydipsia
- Polyphagia
- Weight loss (type 1)
- Weight gain (type 2)
- Vision changes
- Fatigue
RFs of DM
- Genetics
- Age
- Family history
- Unhealthy diet
- Physical inactivity
- Obesity
Major modifiable RFs for DM
- Unhealthy diet
- Physical inactivity 3. Obesity
- High BP
- High Cholesterol
Other modifiable RFs for DM
- Low Socio-economic status
- Heavy alcohol use
- Psychological stress
- High consumption of sugar – sweetened
beverages - Low consumption of fiber
Non-modifiable RFs for DM
- Increased age
- Family history/Genetics
- Race
- Distribution of fat
Other RFs for DM
- Low birth weight
- Presence of autoantibodies
Cancer is also known as?
malignant tumors and neoplasms
generic term for a large group of
diseases due to the rapid creation of abnormal cells that grow beyond their usual boundaries, and which can then invade adjoining parts of the body and spread to other organs
Cancer
Cancer arises from?
transformation of normal cells into tumor cells in a multistage process that generally progresses from a pre-cancerous lesion to a malignant tumor
Causes of cancer
Chemical, Physical and Biological Carcinogen
Person’s genetics
RFs for Cancer
Biomedical factors (Genetic susceptibility, hormonal factors in females)
Lifestyle (Smoking, alcohol, Physical activity, Chronic infections, Diet)
Environmental (sunlight, radiation, occupational exposure, pollution)
Common Oncoviruses
Human T-Lymphotrophic Virus-1 –> T-cell Leukemia
Human Papillomavirus –> Cervical cancer
Hepatitis B and C virus –> Hepatocellular carcinoma
Human Immunodeficiency virus –> Kaposi’s sarcoma and non- Hodgkin’s lymphoma
Epstein-Barr virus –> Burkitt’s lymphoma and nasopharyngeal cancer
EARLY DETECTION OF CANCER through?
- Early diagnosis
- Screening
Steps for early diagnosis of cancer
- Awareness and accessing care
- Clinical evaluation, diagnosis, and staging
- Access to treatment
Examples of Screening Methods for cancer
- Visual inspection with acetic acid (VIA) for cervical cancer in low-income settings
- HPV testing for cervical cancer
- PAP cytology test for cervical cancer in
middle- and high-income settings - Mammography screening for breast
cancer in settings with strong or relatively strong health systems.
diseases of the airways and other structures of the lung
CHRONIC RESPIRATORY DISEASES
Are CHRONIC RESPIRATORY DISEASES curable?
No
CHRONIC RESPIRATORY DISEASES examples
ASTHMA
CHRONIC OBSTRUCTIVE PULMONARY DISEASE
OCCUPATIONAL LUNG DISEASES
PULMONARY HYPERTENSION
common lung condition that causes sporadic breathing difficulties
Asthma
chronic disease where in the lining of the bronchial tubes swell, causing the airways to narrow and reducing the flow of air into and out of the lungs
Asthma
Asthma is common in?
Children
Globally,_____ people currently suffer from asthma
235 million
According to WHO, there were ____ deaths due to asthma in 2015
383 000
lung disease that is characterized by a persistent reduction of airflow
COPD
COPD is caused by?
by a mixture of small airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema)
RFs for COPD?
- Cigarette smoking
- Indoor air pollution (such as solid
fuel used for cooking and heating) - Outdoor air pollution
- Occupational dusts and chemicals
(such as vapors, irritants, and fumes) 5. Frequent lower respiratory
infections during childhood