MT4 - PASTEURELLA - General Flashcards
Asymptomatic carriage of Pasteurella multocida can occur in birds
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Pasteurella multocida is highly resistant; it can survive in the environment for several months
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Pasteurella multocida can cause pasteurellosis in small ruminants
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Pasteurella multocida can infect humans:
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Primary pasteurellosis disease have no predisposing factors
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Non-infectious:
* management, transportation, stress, overcrowding * „primary pasteurellosis”
infectious:
* viruses, mycoplasmas, other bacteria * „secondary pasteurellosis”
Pasteurella multocida can complicate canine distemper.
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Leukotoxin (cytotoxin) production is an important virulence factor of Mannheimia haemolytica
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leukotoxin (cytotoxin)
outer membrane proteins
capsule polysaccharide
The dermonecrotoxin of Pasteurella multocida damages the osteoclast cells:
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osteoblast
Primary pasteurellosis diseases are caused by obligate pathogenic Pasteurella bacteria:
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facultative pathogenic bacteria
Dermonecrotoxin can be virulence factor of Pasteurella multocida:
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- capsule
- LPS (endotoxin)
- dermonecrotoxin
- hyaluronidase production (B)
- outer membrane proteins, adhesins, fimbria
Dermonecrotoxin of pasteurella multocida causes lesions in the nasal cavity and on the skin of pigs
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Capsule can be virulence factor of Pasteurella multocida:
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- capsule
- LPS (endotoxin)
- dermonecrotoxin
- hyaluronidase production (B)
- outer membrane proteins, adhesins, fimbria
Asymptomatic carriage of Pasteurella multocida can occur in bird
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Enterotoxins are virulence factors of Pasteurella multocida
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- LPS (endotoxin)
The agent of acute systemic pasteurellosis is zoonotic:
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Mannheimia haemolytica leukotoxin (cytotoxin) damages the macrophages
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Pasteurella ovis can cause pasteurellosis in small ruminants
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p.multicoida
Arthritis can be a clinical sign of ovine pasteurellosis
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Transportation is a predisposing factor of respiratory pasteurellosis of calves:
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non-infectious:
- management, transportation, stress, overcrowding
- „primary pasteurellosis”
infectious:
- viruses, mycoplasmas, other bacteria
- „secondary pasteurellosis”
Primary pasteurellosis diseases have non infectious predisposing factors
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stress, poor nutrition, environmental conditions, and overcrowding
Emboli are responsible for the necrosis seen in the case of acute systemic pasteurellosis
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Leukotoxin is a virulence factor of Mannheimia haemolytica.
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Capsule is a virulence factor of Pasteurella multocida.
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Leukotoxin is produced by the majority of Pasteurella multocida.
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Produced by Mannehimia haemoytica
Pasteurella multocida can cause disease only in ruminants
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Mannheimia haemolytica can cause disease mainly in ruminants.
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Bibersteinia trehalosi can infect ruminants.
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Pasteurellaceae are resistant bacteria, they remain viable for a long time in the soil
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Low resistance
The virulence factors of P. multocida are the capsule and dermonecrotoxin.
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Pasteurella are very resistant in the environment
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Pasteurella are obligate pathogens
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facultative pathogenic bacteria
We can use inactivated bacteria as a vaccine for Pasteurella
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