MT3- Classical Swine Fever Flashcards
Haemorrhagic enteritis is a characteristic pathological lesion of Classical swine fever
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Classical Swine Fever is frequently complicated with bacterial infections.
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damage of the immune system → bacterial complications
Classical swine fever virus can be transmitted by raw pork products
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live, infected animals
raw pork meat, pork products
raw pork wastes -slaughter
fomites
humans
wild boar!
Classical swine fever virus can retain its infectivity for 6 months in frozen meat
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months or even years!
The CSFV may survive in frozen meat for months
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months or even years!
During necropsy enlarged bloody lymph nodes can be seen in Classical swine fever cases
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Because of endothelial damage Classical swine fever results in haemorrhages
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In acute Classical swine fever, at the beginning obstipation, later diarrhoea can be observed
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Classical swine fever targets the bone marrow stem cells
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Erysipelas and Porcine circovirus 2 infections may cause clinical signs and pathology lesions
similar to CS
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also African swine fever
Weakness of the hind legs and ataxia are clinical signs of Classical Swine Fever
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Ataxia
Paresis, paralysis
Convulsion
Cyanosis
Petechiae
Echymosi
Ischaemic infarcts at the edges of the spleen are postmortem lesions of subacute Classical
Swine Fever
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The boutons in the intestines are characteristic lesions in subacute Classical Swine Fever
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- gastritis
- crupous pseudomembranes
- boutons
Kidney haemorrhage is a characteristic lesion of Classical Swine Fever
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- kidney
- LN
- intestine
- RECTUM
- larynx etc..
Hemorrhages are the most typical lesions of acute CSF
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During necropsy of acute Classical swine fever cases, haemorrhages can be seen in the
gastric mucosa
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Among Classical Swine Fever clinical signs CNS and eye problems can be observed
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- spleen
- stomach
- lungs
- tonsils
- brain
- eyes
- thymus
The CSFV causes central nervous signs only in suckling piglets
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Classical swine fever infection during the first half of pregnancy results in the birth of
immunotolerant piglets
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CSF infection during the first of half of pregnancy can lead to abortion
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Classical swine fever infection in the second half of the pregnancy leads to foetal development problems
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First half
Shedding of Classical swine fever virus starts 1 week after the infection
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The shedding of CSFV begins 1-2 days after the appearance of clinical signs
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The domestic swine population of most European countries are free from CSF
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Classical swine fever causes oronasal infection
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Oronasal route (skin, wounds, conjunctiva, insemination,
fomite contact)
Classical swine fever can be transmitted by mating
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Horizontal transmission
direct /indirect contact
CSF can cause transplacental infections
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CSFV may case reproductive disorders
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Classical swine fever targets lymphatic tissues
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CSF infections result in thrombocytopenia
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damage to the bone marrow stem cells → thrombocytopenia
Clinical signs of Classical Swine fever are mainly seen in 6-12 week old piglets in vaccinated
herds
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Classical swine fever infection during the first half of pregnancy can lead to abortion
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Wild boars play the main role in the maintenance of CSF virus in endemic areas
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Wild boar may play a role in the maintenance and spread of CSFV
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In Europe it is obligatory to vaccinate against Classical swine fever
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Vaccination:
In CSF-free countries, the preventive immunisation is forbidden
In acute Classical swine fever skin haemorrhages and bloody nasal discharge can be observed
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Normal sized spleen can be observed in uncomplicated cases of subacute Classical swine
fever
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Classical swine fever infection results in immunosuppression
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All wild type strains of classical swine fever virus are highly virulent
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Six distinct serotypes of CSF virus are recognized so far
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- can’t find on pp
CSF virus is an arbovirus
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Pestivirus - Flaviviridae family
CSF virus is a zoonotic agent
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Pigs shed CSF virus only during the clinical stage of the disease
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Central nervous signs might be seen in classical swine fever
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Based on pathology and clinical signs, chronic classical swine fever is easy to diagnose
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In vaccinated herds we mostly see the CSF clinical signs in 6-12 weeks old piglets
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