MT3- Classical Swine Fever Flashcards

1
Q

Haemorrhagic enteritis is a characteristic pathological lesion of Classical swine fever

A

T

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2
Q

Classical Swine Fever is frequently complicated with bacterial infections.

A

T

damage of the immune system → bacterial complications

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3
Q

Classical swine fever virus can be transmitted by raw pork products

A

T

live, infected animals
raw pork meat, pork products
raw pork wastes -slaughter
fomites
humans
wild boar!

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4
Q

Classical swine fever virus can retain its infectivity for 6 months in frozen meat

A

T

months or even years!

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5
Q

The CSFV may survive in frozen meat for months

A

T

months or even years!

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6
Q

During necropsy enlarged bloody lymph nodes can be seen in Classical swine fever cases

A

T

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7
Q

Because of endothelial damage Classical swine fever results in haemorrhages

A

T

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8
Q

In acute Classical swine fever, at the beginning obstipation, later diarrhoea can be observed

A

T

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9
Q

Classical swine fever targets the bone marrow stem cells

A

T

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10
Q

Erysipelas and Porcine circovirus 2 infections may cause clinical signs and pathology lesions
similar to CS

A

T

also African swine fever

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11
Q

Weakness of the hind legs and ataxia are clinical signs of Classical Swine Fever

A

T

Ataxia
Paresis, paralysis
Convulsion
Cyanosis
Petechiae
Echymosi

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12
Q

Ischaemic infarcts at the edges of the spleen are postmortem lesions of subacute Classical
Swine Fever

A

T

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13
Q

The boutons in the intestines are characteristic lesions in subacute Classical Swine Fever

A

T
- gastritis
- crupous pseudomembranes
- boutons

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14
Q

Kidney haemorrhage is a characteristic lesion of Classical Swine Fever

A

T

  • kidney
  • LN
  • intestine
  • RECTUM
  • larynx etc..
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15
Q

Hemorrhages are the most typical lesions of acute CSF

A

T

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16
Q

During necropsy of acute Classical swine fever cases, haemorrhages can be seen in the
gastric mucosa

A

T

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17
Q

Among Classical Swine Fever clinical signs CNS and eye problems can be observed

A

T

  • spleen
  • stomach
  • lungs
  • tonsils
  • brain
  • eyes
  • thymus
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18
Q

The CSFV causes central nervous signs only in suckling piglets

A

F

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19
Q

Classical swine fever infection during the first half of pregnancy results in the birth of
immunotolerant piglets

A

T

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20
Q

CSF infection during the first of half of pregnancy can lead to abortion

A

T

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21
Q

Classical swine fever infection in the second half of the pregnancy leads to foetal development problems

A

F

First half

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21
Q

Shedding of Classical swine fever virus starts 1 week after the infection

A

F

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22
Q

The shedding of CSFV begins 1-2 days after the appearance of clinical signs

A

T

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23
Q

The domestic swine population of most European countries are free from CSF

A

T

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24
Q

Classical swine fever causes oronasal infection

A

T

Oronasal route (skin, wounds, conjunctiva, insemination,
fomite contact)

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25
Q

Classical swine fever can be transmitted by mating

A

T

Horizontal transmission
direct /indirect contact

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26
Q

CSF can cause transplacental infections

A

T

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27
Q

CSFV may case reproductive disorders

A

T

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28
Q

Classical swine fever targets lymphatic tissues

A

T

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29
Q

CSF infections result in thrombocytopenia

A

T

damage to the bone marrow stem cells → thrombocytopenia

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30
Q

Clinical signs of Classical Swine fever are mainly seen in 6-12 week old piglets in vaccinated
herds

A

T

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31
Q

Classical swine fever infection during the first half of pregnancy can lead to abortion

A

T

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32
Q

Wild boars play the main role in the maintenance of CSF virus in endemic areas

A

T

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33
Q

Wild boar may play a role in the maintenance and spread of CSFV

A

T

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34
Q

In Europe it is obligatory to vaccinate against Classical swine fever

A

F

Vaccination:
In CSF-free countries, the preventive immunisation is forbidden

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35
Q

In acute Classical swine fever skin haemorrhages and bloody nasal discharge can be observed

A

T

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36
Q

Normal sized spleen can be observed in uncomplicated cases of subacute Classical swine
fever

A

T

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37
Q

Classical swine fever infection results in immunosuppression

A

T

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38
Q

All wild type strains of classical swine fever virus are highly virulent

A

F

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39
Q

Six distinct serotypes of CSF virus are recognized so far

A

F

  • can’t find on pp
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40
Q

CSF virus is an arbovirus

A

F

Pestivirus - Flaviviridae family

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41
Q

CSF virus is a zoonotic agent

A

F

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42
Q

Pigs shed CSF virus only during the clinical stage of the disease

A

F

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43
Q

Central nervous signs might be seen in classical swine fever

A

T

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44
Q

Based on pathology and clinical signs, chronic classical swine fever is easy to diagnose

A

F

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45
Q

In vaccinated herds we mostly see the CSF clinical signs in 6-12 weeks old piglets

A

T

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46
Q

Fomites do not play a role in the transmission of the Classical Swine Fever Virus

A

F

Oronasal route (skin, wounds, conjunctiva, insemination,
fomite contact)

47
Q

Transplacental infection with CSFV may cause immunotolerance in new-born piglets

A

T

48
Q

Swine shed CSFV only in the terminal phase of the disease

A

F

1- 3 months

49
Q

Europe is free from CSFV

A

F

50
Q

Classical Swine Fever is always an acute disease with high mortality in wild boars

A

F. (low mortality)

51
Q

The large intestine are the earliest lesions in Classical Swine Fever

A

F

Paracute:
- brain lymphocytic infiltration
- +/- fine haemorrhage in the kidney cortex

52
Q

The diagnosis of Classical Swine Fever is based on paired serum investigations

A

F

  • RTqPCR
  • Virus isolation
  • IH
  • IF
  • ELISA
53
Q

Porcine circovirus 2 may cause lesions similar to Classical Swine Fever

A

T

54
Q

Low virulence strains of CSFV may cause reproductive problems

A

T??

55
Q

CSFV may damage the lymphatic tissues and blood vessel endothelial cells

A

T

56
Q

Swine can shed CSFV in the incubation period

A

T

57
Q

Skin suffusions and haemorrhages are signs of Classical Swine Fever.

A

T

58
Q

The clinical signs of African Swine Fever and Classical Swine Fever are very different

A

F

59
Q

Contaminated pork meat can play a role in the transmission of CSFV

A

T

60
Q

Attenuated vaccines are developed for immunization of swine against CSFV

A

T

61
Q

All known strains of the Classical Swine Fever virus are of highly virulence

A

F

62
Q

The Classical Swine Fever may appear in a milder form in wild boar than in domestic swine

A

T

63
Q

Erysipelas and Porcine circovirus 2 infections may cause clinical signs and pathology lesions
similar to Classical Swine Fever

A

T

64
Q

Classical swine fever virus is shed with faces, when boutons appear in the intestines

A

F,T ??

  • sheds prior to appearance of clinical signs
65
Q

Classical swine fever can be eradicated from wild boar populations by oral vaccination.

A

F

Experimental, oral vaccination of wild boars in Germany and in Slovakia

66
Q

Classical swine fever virus is rarely complicated by secondary infections

A

F

67
Q

Classical swine fever can be diagnosed easily by the characteristic symptoms and lesions

A

F

68
Q

Domestic swine stocks are free of classical swine fever in most of the European countries

A

T

69
Q

Acute classical swine fever can cause haemorrhagic pneumonia

A

T

70
Q

Classical swine fever virus doesn’t induce neutralizing antibody production

A

F

71
Q

Classical swine fever virus is inactivated in chilled meat at -20°C.

A

F

72
Q

Classical swine fever virus can cause immunotolerance in swine

A

T

73
Q

.Only DIVA vaccines should be used to prevent classical swine fever in swine stocks.

A

F

74
Q

Classical swine fever virus causes lympho-histiocytic encephalitis in pigs.

A

T

75
Q

Classical swine fever virus causes lympho-histiocytic encephalitis in carnivores

A

F

76
Q

Classical swine fever Virus spreads slowly in the host and causes mainly chronic disease

A

F

77
Q

Complicated forms of the Classical swine fever are rarely seen

A

F

78
Q

The Classical swine fever virus may cause reproductive disorders

A

T

absorption, stillbirth, mummification

79
Q

Haemorrhages are the most typical lesions of acute Classical swine fever

A

T

80
Q

Classical swine fever can unambiguously diagnosed by the clinical signs and pathology

A

F

81
Q

Domestic swine of most European countries are free from Classical swine fever virus

A

T

82
Q

The Classical swine fever may appear in a milder form in wild boar than in domestic swin

A

T

83
Q

Low virulence strains of CSFV may lead to asymptomatic infection

A

T

84
Q

CSF is spread via infected pigs

A

T

85
Q

Sows infected by CSF will have immunotolerant piglets.

A

T

86
Q

Piglets of sows vaccinated against CSF are vaccinated at 6-12 months

A

F

87
Q

To prevent CSF, we vaccinate pigs older than 6 months of age with live vaccine

A

F

88
Q

To prevent CSF we use inactivated vaccines made from the Chinese strain

A

F

89
Q

Shedding may start 2-3 days after first clinical signs

A

F

90
Q

CSF can be prevented by inactivated vaccines.

A

F

91
Q

CSF can hardly be distinguished from African swine fever

A

T

92
Q

CSF always causes abortion in pigs

A

F

93
Q

Hungary does not have to make any preventative action against CSF

A

F

94
Q

Incubation of CSF is 8-22 days

A

F

Incubation 4-7 day : Acute infection

Incubation up to 1 month: chronic infection

95
Q

CSF was first written about in USA

A

T (1833)

96
Q

First symptom of CSF is drooping ear

A

F

brain lymphocytic infiltration
+/- fine haemorrhage in the kidney cortex

97
Q

CSF virus has good resistance

A

T

98
Q

Classical swine fever virus (CSFV) is mainly transmitted by mosquitoes

A

F

live, infected animals
raw pork meat, pork products
raw pork wastes -slaughter
fomites
humans
wild boar!

99
Q

The presence of CSFV in a herd does not influence reproduction parameters

A

F

100
Q

CSF is frequently complicated with bacterial infections

A

T

101
Q

The clinical signs of CSF and ASF are similar

A

T

102
Q

Central nervous signs are never seen in CSF

A

F

103
Q

Serological cross reactions my occur between BVD virus and CSFV

A

F

104
Q

Only inactivated vaccines are available against CSFV.

A

F

105
Q

It is a disease of domestic swine and wild boars, but several other species are also suceptible

A

F

106
Q

Only domestic swine and wild boars are susceptible

A

T

107
Q

Fever, anorexia haemorrhages in the skin and weakness of the hind legs are the most important signs

A

T

108
Q

For prevention state medical steps and vaccination are used in Europe

A

F

109
Q

The CSFV typically damages endothelial- and lymphatic tissues

A

T

110
Q

Boutons in the large intestine are the earliest lesions in CSF

A

F

110
Q

In Europe vaccination of domestic pigs against Classical swine fever is common

A

F

111
Q

Classical swine fever is a notifiable disease in Europe

A

T

112
Q

In Europe vaccination of domestic swine populations against CSF is compulsory

A

F

113
Q

Classical swine fever virus strains are classified into several serotypes

A

F

114
Q

In subacute CSF we can observe signs of pneumonia during necropsies

A

T