Arteriviruses Flashcards
Arterivirus, the virulence is highly variable
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The equine viral arteritis is caused by an arterivirus.
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Serological tests can NOT be used for laboratory detection of equine viral arteritis
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- Serology: VN (1:4), ELISA (gp5)
ed blood cells can be used for laboratory detection of equine viral arteritis virus
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Samples: nasal fluid, WBC, semen, caul
Nasal fluid can be used for laboratory detection of equine viral arteritis virus
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A semen sample can be used for laboratory detection of equine viral arteritis virus
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Equine arteritis virus is very resistant to physical damages
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Low resistance in environment
Equine viral arteritis is usually asymptomatic
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In cases of equine viral arteritis, the rate of seroconverted animals increases with age
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The main target cells of equine viral arteritis are macrophage
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Replication: Macrophages, endothelialcells, vascular smooth muscle cells
Equine Viral arteritis (EVA) virus can affect donkeys
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horses, ponies, donkeys and zebras (South american Camelids)
The persistence of EVA virus within one herd is usually caused by the stallions
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persistent infection in mature animals
EVA is transmitted by sexual and aerogenic pathways
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sexual transmission: 1 week
After EVA virus infection, mortality rate is low
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Equine arteritis virus is very resistant to physical damage
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Low resistance in environment
Equine viral arteritis is usually asymptomatic
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The main target cells of equine viral arteritis virus are macrophages
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EVA can affect donkeys
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horses, ponies, donkeys and zebras
EVA can cause persistent virus carrying.
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persistent infection in mature animals
After EVA infection mortality rate is low
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Equine Viral Arteritis virus can infect by inhalation
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Vaccine against Equine Viral Arteritis is never used in Europe
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Inactivated (in EU) 2X
The Equine Viral Arteritis is caused by retrovirus
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Arteriviridae Family
The equine viral arteritis virus cannot damage the wall of blood vessel
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Damage of blood vessel walls (inflammation in the endothel and media)
The equine viral arteritis virus usually causes asymptomatic infection
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The equine viral arteritis virus can cause persistent infections
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persistent infection in mature animals
The equine viral arteritis virus always causes clinical symptoms
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- usually asymptomatic
EVA is spread by insect vectors
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venereal, nasal (per os)
Equine viral arteritis causes reproductive problems/impotence in stallions.
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Acute equine viral arteritis is similar to Equine infectious anaemia
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Equine viral arteritis in mare is reactivated in pregnancy
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Equine viral arteritis, aborted embryos have degenerated liver
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- Fibrinoid degeneration
- inflammation and thrombus formation in small blood vessels
- Interlobular interstitial pneumonia
- Fibrinoid-necrotic enteritis
Mares are frequently life-long carriers of the Equine arteritis virus.
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Stallions: long term carriers (10-70%)
Subcutaneous oedema is a frequent sign of equine viral arteritis
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Pregnant mares usually abort in the acute phase of equine viral arteritis
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Equine viral arteritis is diagnosed by agarose-gel immunodiffusion (Coggins test)
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- Clinical signs, pathology
- Samples: nasal fluid, WBC, semen, caul
- Isolation (CPE), IF, IHC, RT-PCR (semen)
- Serology: VN (1:4), ELISA (gp5)
The Equine arteritis virus may cause abortion in pregnant mares
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Vaccination of colts before puberty can prevent the development of EAV-carrier status
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Stallions may be long-term carriers of the Equine arteritis virus
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Stallions: long term carriers (10-70%), semen (for years),
Conjunctivitis and subcutaneous oedema are possible signs of equine viral arteritis.
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Equine viral arteritis virus can infect through nasal route
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Equine viral arteritis virus can infect per os
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Equine viral arteritis virus can infect through venereal way.
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venereal, nasal (per os)
Equine viral arteritis virus can infect only by arthropods
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venereal, nasal (per os)
Equine arteritis virus is a uniform virus without serotypes, subtypes etc
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1 serotype
Aerogenic infection can happen in the case of equine arteritis virus
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Equine arteritis virus is shed in the semen
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Equine arteritis virus can cause abortion
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Equine arteritis virus is very resistant to physical damage
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Low resistance in environment
In case of equine viral arteritis, the rate of seroconverted animals increases with age
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Lameness due to inflammatory joints is the most typical sign of Equine infectious arteritis
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Equine infectious arteritis is a notifiable disease; therefore vaccinations are forbidden
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- Inactivated (in EU) 2X
- Attenuated =MLV (in USA, Canada)
- Eradication
The persistence of equine viral arteritis virus within one herd is usually caused by the
stallions
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Equine viral arteritis is transmitted by a sexual and aerogenic pathways
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After equine viral arteritis virus infection, mortality rate is low
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Equine infectious arteritis is a notifiable disease
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The main target of Equine viral arteritis virus is macrophages.
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Equine infectious arteritis is stenoxen viruses
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Equine viral arteritis can be controlled in part by removing long-term carriers
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Equine viral arteritis can affect donkeys
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- horses, ponies, donkeys and zebras
PRRS is caused by an arterivirus.
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PRRS is caused by a coronavirus
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- arterivirus.
The clinical signs of PRRS can be abortion like that of SMED
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- Respiratory in young
- Abortion, return to estrus in sows
Isolation of PRRS in cell culture can be easily performed in any laboratory
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PRRS has only highly pathogenic variants
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Respiratory signs of PRRS occur just in sows
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PRRS virus replicates in macrophages
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PRRS virus replicates in T-lymphocytes
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The pathological signs of PRRS is typical because the lymph nodes are never enlarged
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Periocular edema, interstitial pneumonia, enlarged lymph nodes
PRRS virus affects the respiratory system in young piglets
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PRRS cause digestive sign in adult
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PRRS has 2 phases
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PRRS cause respiratory sign in adult
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Target cells of PRRSV are alveolar epithelial cells
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PRRS can only be isolated in porcine kidney cells.
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PRRS causes immune suppression in prolonged cases
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Attenuated and inactivated vaccines are available against PRRS
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PRRS virus causes severe intestinal problems in adult pigs
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Periocular edema, interstitial pneumonia, enlarged lymph nodes
PRRS is characterized by respiratory disease in adult pigs
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PRRS infection has 2 clinical phases
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PRRSV attacks the active macrophages
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For PRRS prevention we can get a very good immunization with inactivated vaccines
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PRRS: reproductive and respiratory problems and others with other virulence
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Maternal immunity protects only short time against PRRS
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Porcine reproductive and respiratory virus (PRRSV) can cause abortion only in the advanced
stage of pregnancy (over 90 days).
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Only inactivated vaccines can be used for the prevention against PRRSV
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- vaccination
- eradication
Porcine reproductive and respiratory virus (PRRSV) propagates in lymphatic cells
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PRRSV infection may influence the reproductive performance of boars
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Porcine reproductive and respiratory virus (PRRSV) is a zoonotic agent
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Porcine parvoviruses and PRRSV may cause similar disease in sows
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Porcine reproductive and respiratory vines (PRRSV) does not cause clinical signs in boars.
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Inactivated vaccines alone cannot induce protective immunity against PRRSV
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Boars can transmit porcine reproductive and respiratory syndrome virus in the semen
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Porcine reproductive and respiratory syndrome virus cannot cause abortion, only infertility
of the sows
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There are no vaccines for the prevention of Porcine reproductive and respiratory syndrome.
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The blue ear disease is caused by dog coronavirus
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PRRS
The blue ear disease is caused by FIP
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- PRRS
The blue ear disease is caused by chicken coronavirus.
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- PRRS
The blue ear disease is caused by PRRS
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Does PRRS virus have 3 genotypes.
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- 2 Genotypes
Oedema can be a sign of PRRS.
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PRRS is deadly in adult animals
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Target cells of PRRSV are alveolar epithelial cells.
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- macrophage
PRRS virus can only be isolated in porcine kidney cell culture
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The Porcine reproductive and respiratory syndrome (PRRS) is only present in NorthAmerica
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The PRRS virus may cause reproductive problems in boars
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PRRS: cyanosis is one clinical symptom
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- Simian Hemorrhagic Fever Virus