MSK Flashcards
Using TIM, which conditions must be excluded before an MSK complaint is discharged?
Tumour/trauma
Infection/inflammation
Malignancy/Mechanical/Metabolic
What is the function of osteoblasts?
Produce osteoid composed of type 1 collagen, mineralization of matrix
What is the function of osteoclasts?
Remove bones tissue by removing mineral matrix and breaking organic bone
How are synovial joints composed?
Covered by hyaline cartilage with joint space enclosed by synovium
How does an inflamed synovium affect bone?
Excessive fluid with altered cells and increased cytokines = destroys hyaline cartilage then bone
What is an enthesis?
Point of insertion of tendon, ligament, fascia or joint capsule into bone, prone to stresses
Give one example of an inflammatory and non-inflammatory primary muscle disease
I: dermatomyositis
NI: Muscular dystrophy associated with calf hypertrophy
What is Gower’s sign and which condition is it strongly associated with?
Functional weakness seen classically in DMD where pt. uses hands to splint legs to help them rise from sitting
Give 4 MSK history red flags
- Unable to sleep, unremitting pain
- Deep pain unresponsive to pain relief
- Loss of function or altered function
- Unilateral
What are the top 3 organisms implicated in septic arthritis?
Staph aureus
Strep. pneumo
Haem influenza
How may a joint appear in septic arthritis?
Hot Swollen Exquisitely painful Red Held immobile
In neonates, what is pseudoparalysis until proven otherwise?
Bone/joint sepsis
Give 4 Tx steps in septic arthritis
- ABC and resus
- Urgent aspirate
- Blood cultures x2
- IV ABX
How does osteomyelitis classically present?
Acutely unwell child
Pyrexia
Local erythema + tenderness
Give 3 Tx steps in osteomyelitis
- Blood cultures
- High dose IV ABX
- Splintage of limb
Which disease can be cause of insidious onset septic arthritis/osteolitis with vertebral involvement?
Tuberculosis
What is the cause and Tx of rheumatic fever?
Strep. infection
Tx: penicillin
What is Reiter’s syndrome?
Post enteric/GU infection after gram negative/STI infection
How does irritable hip present?
Hip pain and limp
Hip flexed and externally rotated
How does the self-limiting condition discitis present ?
Child refuses to walk
Low grade fever
Lumbar spine tenderness
What is Juvenile Idiopathic Arthritis?
Group of conditions where investigation aims to rule out other diagnoses
Which conditions occurs in JIA patients and can cause blindness?
CHRONIC ANTERIOR UVEITIS
Name 2 types of vasculitis common in children
o Henoch Schonlein purpura (HSP)
o Kawasaki disease
Which types of Salter-Harris fractures should always be referred to ortho and why?
Type III and IV
Intra-articular with high risk of growth impairment and need for surgery
Name 3 types of fractures which occur in children and not adults
Greenstick
Buckle
Plastic deformation
What is Legg-Calve-Perthes disease?
Necrosis of part of femoral capital epiphysis (growth disturbance which can cause degenerative joint disease)
How does Legg-Calve-Perthes disease present and what is the Tx?
Knee pain, limp, reduced hip abduction and internal rotation
Tx: rest/casts/surgery
Which condition can occur when a child rapidly grows or is obese?
Slipped upper femoral epiphysis (SUFE
Name 3 risks of Developmental dysplasia of the hip
- 1st degree relative
- Female
- Breech after 35 weeks
How is Developmental dysplasia of the hip treated at birth?
Splintage in abduction for 12 weeks
Which deformities are seen in Talipes equinovarus (club foot)?
- Downward and inward heel
- Soles point medially
What is scoliosis?
-Lateral curvature of spine, presenting at time of accelerated growth in puberty
Give 4 back pain red flags
- Under 4y/o
- Night pain
- Functional disability
- Postural shift
What are the 5S’s of normal variants in children?
- Symmetrical deformity
- No symptoms underlying systemic disease or skeletal dysplasia
- No stiffness on examination
Name 3 benign conditions in children
- Osgood Schlatter’s
- Irritable hip
- Pulled elbow
Name 2 conditions in which muscle enzymes like CK, LDH, AST/ALT may be elevated?
Muscular dystrophy
Inflammatory disease
What is the significance of ANA in JIA children?
Majority of ANA negative
Name 2 pathologies which plain X-rays are good at assessing
Hip pathology
NAI
Which sign is seen in DMD whereby patients use their arms to splint their legs to aid standing?
Gower’s sign