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PHM 701- MS, HA, Stroke, Sleep > MS- Natalizumab DI > Flashcards

MS- Natalizumab DI Flashcards

1
Q

Natalizumab brand name

A

Tysabri

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2
Q

Tysabri indications

A

CIS, active SPMS, RRMS

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3
Q

Tysabri MoA

A

Antagonizes alpha-4-integrin of the adhesion molecule VLA-4 on leukocytes

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4
Q

Tysabri dosing

A

300mg IV infusion q4weeks

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5
Q

Tysabri ADEs

A

PML!!!!!

Infusion site reactions, including hypersensitivity reasons
Respiratory tract infections
UTIs
Depression
HA
Fatigue
Diarrhea
Cholelithiasis
Arthralgia

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PHM 701- MS, HA, Stroke, Sleep (63 decks)

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