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PHM 701- MS, HA, Stroke, Sleep > HA- CGRP MAb DI > Flashcards

HA- CGRP MAb DI Flashcards

1
Q

CGRP MAbs used in HA treatment

A

Eptinezumab, erenumab, fremanezumab, galcanezumab

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2
Q

Eptinezumab brand name

A

Vyepti

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3
Q

Erenumab brand name

A

Almovig

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4
Q

Fremanezumab brand name

A

Ajovy

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5
Q

Galcanezumab brand name

A

Emgality

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6
Q

Eptinezumab indication

A

Migraine PREVENTION

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7
Q

Erenumab indication

A

Migraine PREVENTION

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8
Q

Fremanezumab indication

A

Migraine PREVENTION

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9
Q

Galcanezumab indications

A

Migraine PREVENTION and PREVENTION OF CLUSTER HA

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10
Q

Eptinezumab route of administration and frequency

A

IV q3months

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11
Q

Erenumab route of administration and frequency

A

SQ qmonth

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12
Q

Fremanezumab route of administration and frequency

A

SQ month or q3months

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13
Q

Galcanezumab route of administration and frequency

A

SQ qmonth

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14
Q

Eptinezumab ADEs

A

INFUSION reaction, nasopharyngitis, nausea

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15
Q

Erenumab ADEs

A

Injection site reaction, constipation

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16
Q

Fremanezumab ADE

A

Injection site reaction

17
Q

Galcanezumab ADE

A

Injection site reaction

18
Q

CGRP MAb DDI

A

Few drug interactions (specifically efgartigimod)

19
Q

CGRP MAb warning/precaution

A

Caution in patients with recent CV or cerebrovascular ischemic events

20
Q

CGRP MAb half-life

A

Around 28-32 days

21
Q

Adequate trial of eptinezumab

A

≥6 months

22
Q

Adequate trial of erenumab, fremanezumab, galcanezumab

A

≥3 months

PHM 701- MS, HA, Stroke, Sleep (63 decks)

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