HA- ADs DI Flashcards
ADs used in HA treatment
Amitriptyline, nortriptyline, venlafaxine
ADs indication in HA treatment
Migraine PREVENTION
ADs BBW
Increased suicidality
ADs adequate trial for migraine treatment
2-3 MONTHS
Amitriptyline, nortriptyline drug class
TCAs
TCA MoA
Increases synaptic concentration of serotonin and/or NE in the CNS by inhibition of their reuptake by the presynaptic neuronal membrane pump
TCA ADEs
Anticholinergic effects, CNS depression, cardiac conduction abnormalities, orthostatic hypotension, serotonin syndrome
Venlafaxine drug class
SNRI
Venlafaxine MoA
Serotonin and NE reuptake inhibitor
SNRI side effects
CNS depression, weight loss, anorexia, increased blood pressure, hepatototixicty, hyponatremia, acute angle closure glaucoma, serotonin syndrome