HA- ADs DI Flashcards

1
Q

ADs used in HA treatment

A

Amitriptyline, nortriptyline, venlafaxine

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2
Q

ADs indication in HA treatment

A

Migraine PREVENTION

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3
Q

ADs BBW

A

Increased suicidality

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4
Q

ADs adequate trial for migraine treatment

A

2-3 MONTHS

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5
Q

Amitriptyline, nortriptyline drug class

A

TCAs

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6
Q

TCA MoA

A

Increases synaptic concentration of serotonin and/or NE in the CNS by inhibition of their reuptake by the presynaptic neuronal membrane pump

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7
Q

TCA ADEs

A

Anticholinergic effects, CNS depression, cardiac conduction abnormalities, orthostatic hypotension, serotonin syndrome

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8
Q

Venlafaxine drug class

A

SNRI

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9
Q

Venlafaxine MoA

A

Serotonin and NE reuptake inhibitor

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10
Q

SNRI side effects

A

CNS depression, weight loss, anorexia, increased blood pressure, hepatototixicty, hyponatremia, acute angle closure glaucoma, serotonin syndrome

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