motivation Flashcards

1
Q

what is the purpose of motivated behaviour?

A

to satisfy a need

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2
Q

ecto vs. homeo therms

A

amphibians, reptiles, fish are cold blooded

mammals and birds are warm blooded

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3
Q

what do thermoreceptors cause?

A
  • increased firing rate to heat stimuli
  • increased firing rate to cold stimuli
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4
Q

where are thermoreceptors located, how are they prioritized?

A

CNS (hypothalamus)
hypothalamus -> body core -> skin

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5
Q

where are temperature sensitive cells in the hypothalamus located?

A

preoptic area (POA)

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6
Q

what does the POA do?

A

regulates temperature
- focuses on the temperature of the brain

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7
Q

what is the carotid artery?

A

major blood vessel that provides brain blood supply, temperature of this controls brain’s response to heat/cool body

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8
Q

what are the 3 ways that the hypothalamus may respond to changes in set point?

A
  • humoral
  • visceromotor
  • somatic motor
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9
Q

what is the humoral reaction?

A

stimulates/inhibits the release of pituitary hormones into the blood stream

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10
Q

what is a visceromotor reaction?

A

balance of sympathetic and parasympathetic outputs in the ANS

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11
Q

what is a somatic motor output?

A

directly infuence actions
“what we physically are going to do to get back to set point”

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12
Q

what occurs when there is a lesion to the POA?

A

loss of thermoregulation

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13
Q

what are the mechanisms behind fever?

A

pyrogens increase set point which leads to body getting hotter

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14
Q

what is the lipostatic hypothesis?

A

brain measures and maintains a body fat level against external conditions and leptin might be the signal that lets brain know about fat storage

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15
Q

what does leptin help do?

A

control eating

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16
Q

how does leptin work?

A

1) produced by fat, in levels proportional to fat
2) receptors are in arcuate nucleus of hypothalamus
3) periventricular zone detects leptin
4) lateral hypothalalmus incites feeding behaviour

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17
Q

what does a lesion to the lateral hypothalamus cause?

A

decrease in hunger -> aphagia

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18
Q

what does a lesion to the ventromedial hypothalamus cause?

A

increase in hunger -> hyperphagia

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19
Q

what does the lateral hypothalamus control?

A

hunger

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20
Q

what does the ventromedial hypothalamus cause?

A

satiety

21
Q

name anorectic peptides?

A

AMUSHCART
- alphaMSH
- CART

22
Q

name orexigenic peptides

A

AMON

  • agRP
  • MCH
  • Orexin
  • NPY
23
Q

anorexic vs. orexigenic peptides

A

anorexic - decrease appetite
orexogenic - increase appetite

24
Q

where does leptin bind to leptin receptors?

A

the arcuate nucleus

25
Q

what does bariatric surgery do?

A

decreases the size of the stomach
- leads to long term weight loss

26
Q

what are the 3 phases of eating?

A

before, during and after

1) cephalic: sight/smell of food drive eating, parasympathetic NS activated -> secretion of saliva into mouth and digestive juices into stomach

2) gastric: stronger responses as you eat, want food as you are tasting it

3) intestinal: stomach fills, food moves to intestines, nutrients begin to absorb

27
Q

what promotes eating in the short term?

A
  • the sequence of eating
  • ghrelin
28
Q

what is ghrelin?
what does it activate?

A

peptide released by empty stomach into blood stream
- activates: NPY and AgRP neurons that increase hunger

29
Q

what inhibits eating in the short term?

A

gastric distention
- stretching of stomach walls by food (mechanosensory axons)
- activates vagus nerve which signals to CNS -> inhibits feeding

CCK
- peptide in cells of intestines and enteric system
- activates vagus nerve and supresses feeding

30
Q

what is prader-will syndrome?

A

obesity due to high ghrelin levels

31
Q

hunger vs. full hormones?

A

ghrelin=hunger
CCK=fullness

32
Q

when are ghrelin and CCK levels high vs. low?

A

start eating
- ghrelin=high
- CCK=low

stop eating
- ghrelin=low
- CCK=high

33
Q

what does THC cause?

A
  • surge in ghrelin levels
34
Q

what is hypovolemia?

A

decrease in blood volume that leads to volumetric thirst

35
Q

what is hyertonicity?

A

increase of blood tonicity that leads to osmometric thirst

36
Q

what is ADH, where is it released?

A

hormone that increases thirst
- released in the hypothalamus

37
Q

what is the visceromotor response to hypovolemia?

A

increase sympathetic activity
- constrict blood vessels to increase blood pressure

38
Q

what is the somatic response to hypovolemia?

A

increase motivation to seek and consume water

39
Q

what is angiotensin II detected by?

A

subfornical organ

40
Q

diabetes insipidus?

A

insufficient ADH or kidney response to ADH
- leads to excessive thirst and dilute urine
- water is not retained

41
Q

Medial preoptic area of hypothalamus?

A

Responds to temperature and mediates humoral + visceromotor response (NOT somatic motor b/c lateral hypothalamus responsible for this)

42
Q

Arcuate nucleus of hypothalamus?

A

Responds to blood levels of leptin and ghrelin

43
Q

Paraventricular nucleus of hypothalamus?

A

Involved in long-term regulation of eating (release hypophysiotropic hormones, receives input from arcuate nucleus, affects sympathetic ANS)

44
Q

Nucleus of solitary tract (gets input from vagus nerve)?

A

Responds to gastric distension signals of stomach (eating) Responds to mechanoreceptors in blood vessel walls (drinking)

45
Q

Subfornical organ?

A

Responds to elevated angiotensin II blood levels (drinking) b/c outside blood brain barrier (BBB)

46
Q

OVLT?

A

Responds to tonicity of blood b/c outside BBB

47
Q

Suprachiasmatic nucleus of PVZ (hypothalamus)?

A

Mediates circadian rhythms

48
Q

Supraoptic nucleus of PVZ (hypothalamus)?

A

Contains magnocellular secretory neurons

49
Q

What are high solute levels detected by?

A

Vascular organ of laminate OVLT