Moses- Depressive Disorders Flashcards

1
Q

Leading cause of disability and premature death in people aged 18 to 44 years.

A

Major Depressive Disorder

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2
Q

The prevalence of MDD is among patients with chronic medical illnesses.

A

30-50%

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3
Q

Up to of adults will have an episode of depression in their lifetime.

A

one-quarter

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4
Q

What are some factors that are related to depression?

A
  • Gender
  • Age
  • Marital Status
  • Mental Health Diagnosis
  • Biological Factors
  • Genetic Factors
  • Psychosocial Factors
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5
Q

More severe major depressive illness occurs with those that begin with depression earlier/later in their lifetime?

A

earlier

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6
Q

What age group is at greatest risk for depression?

A

elderly

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7
Q

What are 5 high risk populations for depression?

A
  • Postpartum Women
  • Personal/Family History of MDD
  • Advanced Age
  • Neurologic Disorders
  • Comorbid Systemic Physical Illness
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8
Q

What are the 6 main depressive orders in the DSM?

A
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9
Q

What is the timeline criteria for persistent depressive disorder (dysthrhymia)?

A

longevity of 2+ years

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10
Q

Which depressive disorder is characterized by an irritated and angry mood?

A

Disruptive Mood Dysregulation Disorder

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11
Q

What is the time criteria for PMDD?

A

symptoms 1 week before and after starting period. 2 weeks on and 2 weeks off

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12
Q

How many symptoms must be present, what is the timeline criteria, and what needs to be noted about baseline functioning for a diagnosis of MDD?

A

5+ criteria met

same 2 week period

change (decrease) in baseline functioning- KEY piece

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13
Q

Review the criteria for MDD

A
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14
Q

What is the acronym that lists the clinical features of MDD?

A

SIGECAPS

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15
Q

Screening tools are used to help with and

A

diagnosis and treatment

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16
Q

What is the most common screening tool for depression?

A

PHQ-9

17
Q

What is the screening tool most commonly used for Post Partum depression?

A

Edinborough Depression Scale

18
Q

List the scores for the following screening tool criteria to be met?

  • Mild Depression: Score
  • Moderate Depression: Score
  • Moderately Severe Depression: Score
  • Severe Depression: Score
  • Greater than or equal to considered a positive screen.
A
  • Mild Depression: Score 5-9
  • Moderate Depression: Score 10-14
  • Moderately Severe Depression: Score 15-19
  • Severe Depression: Score 20-27
  • Greater than or equal to 10 considered a positive screen.
19
Q

There is/is not a huge overlap with major depression and medical illness?

A

is

Examples: endocrine/thyroid issues, cancer, sleep apnea, nutritional deficiencies

20
Q

What are the 2 major classes of drugs most commonly used to treat MDD?

A

SSRIs

SSNRIs

21
Q

Why is fluoxetine most commonly used if there is a risk for non-compliance?

A

longest half-life

22
Q

What are some reasons to use and not use Mirtazipine?

And what populations does this medicine work well and not well

A

helps with sleeping and eating (great for elderly and weight gain)

not good for young adult females

23
Q

Which antidepressant works well as an adjunct for the tx of resistant depression and as a tx for kids with ADD?

A

bupropion

24
Q

What are some common side effects of antidepressants?

A

sexual dysfunction/ decreased libido, weight gain, sedation

25
Q

What is the method of discontinuing use of antidepressants?

A

titrate down, do not stop cold turkey

26
Q

Describe the treatment goal of MDD?

A

remisson of symptoms, titrate to the max dose possible that keeps symptoms under control

27
Q

How long does it usually take to see benefit of antidepressant, and to see real changes?

A

up to 4 weeks for benefit

up to 3-6 mnths for real changes

28
Q

What is the timeline criteria for maintenance of medications?

A

stay on board for 4, 9, even 12 mnths after the remission of symptoms

(because of risk of relapse w/in first 6 mnths)

29
Q

What are 2 non pharmacological first line treatments that can be used for mild depression?

A
  • Interpersonal Psychotherapy
  • Cognitive Behavioral Therapy
30
Q

Which non pharmacological tx are mainly used for tx resistant depression?

A
  • Transcranial Magnetic Stimulation (TMS)
  • Electroconvulsive Therapy (ECT)
31
Q
A