Morphology

Question 1

What cell is this

Answer 1

Megakaryocyte

Question 2

What abnormality is shown here and what can casue it?

Answer 2

Hypersegmented neutrophil

Caused by Vit. B12/folate deficiency

Question 3

What does this blood film show

Answer 3

Normal RBCs

Question 4

What abnormality is shown here, and what are the causes

Answer 4

Spherocytes

Caused by RBC membrane defects, such as Herdeitary spherocytosis and haemolysis

Question 5

What is the difference between normal RBCs and spherocytes?

Answer 5

Spherocytes don’t have the central pallor, they are deformed and have a smaller diameter

They can also lead to the destruction of the spleen

Question 6

Spherocytes and microcytic RBCs both have a decreased cell diameter, but what is the main difference between the two other than the buggered shape?

Answer 6

Microcyitic RBCs still have their central pallor

(unlike spherocytes)

Question 7

What abnormality is this

Answer 7

Microcytic RBCs

Question 8

What is the proper name for Teardrop cells on a blood film?

Answer 8

Dacrocytes

Question 9

What abnormality is shown hear and what is a potential cause

Answer 9

Tear-drop RBCs (dacrocytes)

Potential cause -> myleofibrosis

Question 10

What abnormality is shown here and what are some potential causes

Answer 10

Cabot Ring

Potentially causes: Vit. B12 deficiency & myleofibrosis

Question 11

What 2 abnormalites are shown here, and what is a potential cause

Answer 11

Target cells and Spur cells

Potential casue -> microcytic anaemia due to Crohns

Question 12

What is the proper name for spur cells?

(mon the spurs ehhhhhh)

Answer 12

Acanthocytes

Question 13

What abnormality is shown here

Answer 13

Spur cells (acanthocytes)

Question 14

What is the proper term for sickle cells

Answer 14

Drepanocytes

Question 15

What abnormality is shown here

Answer 15

Sickle cells

(drepanocytes)

Question 16

What is another name for RBC fragments?

Answer 16

Schistocytes

Question 17

What are Helmet cells a type of?

Answer 17

Schistocytes

Question 18

What abnormality is shown here and what is a potential cause

Answer 18

Schistocytes (inlcuding helmet cells)

Causes -> Thrombotic Thrombocytopenic Purpura (TTP)

Question 19

What happens to the platlet count if there are lots of schisocytes (like in TTP)?

Answer 19

It falsely increases

Because automated cell counters think that the schistocytes look like platlets LOL

Question 20

What abnromality is shown here, what is the name of the cells and what is the likley cause?

Answer 20

Oxidative haemolysis

Shows ‘Blister’ cells

Potential cause is G6PD deficiency

Question 21

What abnormality is shown here

Answer 21

RBC Agglutination

Question 22

What cell is this on a blood film, and what condition is present

Answer 22

Myeloblasts

Myeloid malignancy (cause there’s Auer Rods)

Question 23

What is a potential sign of myeloid leukaemias on myeloblasts?

Answer 23

Auer Rods

Question 24

What cell is this

Answer 24

Lymphocyte