Haemo pharmacology Flashcards

1
Q

What are the 2 main types of anti-thrombotic drugs?

A

Anti-platelets

Anti-coagulants

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2
Q

Give 4 examples of anti-platelets

A

Aspirin
Clopidogrel
Ticagrelor
Tirofiban

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3
Q

Aspirin is an anti-platelet drug. What does it inhibit to carry our it’s function?

A

Cycloxygenase (COX)

So it inhibits the catalyst of the reaction between ADP and adrenaline to form arachidonic acid

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4
Q

Clopidogrel and Ticagrelor are both anti-platelet drugs. What does it inhibit to carry our it’s function?

A

Binding of ADP and adrenaline

So arachidonic acid can’t form lol

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5
Q

Tiofibam is an anti-platelet drug. What does it inhibit to carry our it’s function?

A

Glycoprotein binding

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6
Q

Give 3 examples of anti-coagulants?

A

Warfarin
Heparin
Rivaroxoban

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7
Q

Warfarin is an anti-coagulant drug. What factors does it inhibit to carry out its function?

A

F7
F9
F10

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8
Q

Heparin and Riaroxaban are both anticoagulants. What factor do they both inhibit to carry out their function?

A

F10a

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9
Q

What increases APTT, heparin or warfarin?

A

Heparin

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