Haemo pharmacology Flashcards
What are the 2 main types of anti-thrombotic drugs?
Anti-platelets
Anti-coagulants
Give 4 examples of anti-platelets
Aspirin
Clopidogrel
Ticagrelor
Tirofiban
Aspirin is an anti-platelet drug. What does it inhibit to carry our it’s function?
Cycloxygenase (COX)
So it inhibits the catalyst of the reaction between ADP and adrenaline to form arachidonic acid
Clopidogrel and Ticagrelor are both anti-platelet drugs. What does it inhibit to carry our it’s function?
Binding of ADP and adrenaline
So arachidonic acid can’t form lol
Tiofibam is an anti-platelet drug. What does it inhibit to carry our it’s function?
Glycoprotein binding
Give 3 examples of anti-coagulants?
Warfarin
Heparin
Rivaroxoban
Warfarin is an anti-coagulant drug. What factors does it inhibit to carry out its function?
F7
F9
F10
Heparin and Riaroxaban are both anticoagulants. What factor do they both inhibit to carry out their function?
F10a
What increases APTT, heparin or warfarin?
Heparin