Haemophilia Flashcards
What type/pattern of bleeding occurs in haemophilia?
Platelet type
Does haemophilia casue splenic infarction?
Nope, it’s SCD that does that bro
What are the 2 types of haemophilia and which clotting factor is deficient in each one?
Haemophilia A -> F8 deficieincy
Haemophilia B -> F9 deficiency
Which sex are the only ones who can get haemophilia?
Boys
Cause it’s X-linked recessive, and boys only have one X chromosome so it’s always affected
(X-linked conditions need to be dominant for them to affect girls too)
What mode of inheiratnce is haemophilia?
X-linked recessive
Do both types of haemophilia have the same phenotype
Aye that’ll be true
What is the most common type of hameophilia?
Type A (F8 deficiency)
What is another name for Type B haemophila (F9 deficiency)?
Christmas disease
What are the clinical features of haemophilia?
Spontaneous bleeding
Haemathrosis
Muscle haematoma
Post-surgical bleeding
Compartment syndrome
What is haemathrosis?
Bleeding into a joint cavity
What symtpoms does haemathrosis cause?
Joint pain
Swelling
Difficulty weight-bearing
Which joints are most commonly affected by haemathrosis in haemophila?
Knee & ankle
Which muscle is most commonly gets a haematoma in hameophilia?
Iliopsoas
What causes compartment syndrome in haemophila?
Bleeding into muscle and nerve compartments causing pressure
Between which ages is haemophilia diagnosed?
6months -> 2 years
(early on bro)
