Molecular Representation Flashcards
What type of functional group is this?
Alcohol
A carbon atom become an anion when it has how many bonds?
3 bonds and a lone pair
What type of functional group is this?
Carboxylic Acid
What type of funtional group is this ?
Alkyene
What functional group is this?
Amide
What type of functional group is this?
Aldehyde
What type of functional group is this?
Keytone
Lead compound
The known compound that leads the way to other similar compounds
What type of functional group is this ?
Ester
Auxophore
Refers to the rests of the compound that arent responsible for the analgesic activity
Nitrogen atoms are cation when they have how many bonds?
4 bonds
What are the five patterns to recognize when drawing resonance structures?
- Lone pair on the outside (allylic lone pair)
- Lone pair near a positive charge that is on the outside (An allylic postive charge)
- Lone pair (negative charge) near a positive charge
- A double bond connected to an electromegative atom
- Aromatic (Ring) alternating double bonds
Allylic Position
The outer atoms that are directly connected to those carbons
Pharmacphore
Portions of the compound responsible for the analgesic activity
Haworth Projection
Used for Cyclic Compounds
Nitrogen atoms are anions when they have how many bonds?
2 bonds and 2 lone pairs
Localized lone pairs
Lone Pairs that don’t participate in resonance
Delocalization
Spread of a charge & is a stablizing factor
What type of functional group is this?
Ether
What type of functional group is this ?
Alkyl Halide
What type of functional group is this?
Acyl Halide
Halogens are cations when they have how many bonds?
2 bonds & 2 lone pairs
What type of functional group is this?
Aromatic
Halogens are anions when they have how many bonds?
no bonds all lone pairs
Nitrogen atoms are neutral when they have how many bonds?
3 bonds & one lone pair
Oxygen atoms are neutral wehn they have how many bonds?
2 bonds & 2 lone pairs
A carbon atom becomes a cation when it has only how many bonds?
3 bonds
Halogens are neutral when they have how many bonds?
1 bond & 3 lone pairs
Oxygen atoms are anions when they have how many bonds?
1 bond and 3 lone pairs
What type of functional group is this ?
Thiol
Oxygen atoms are cations when they have how many bonds?
3 bonds and 1 lone pair
Vinylic Positions
Carbons that share a double bond
A carbon atom is neutral when it has how many bonds?
4 bonds
What type of molecular represenation is this?
Condensed Structure
What are the rules for breaking curved arrows for resonance structure?
- Avoid breaking a single bond
- Never exceed an octect for second - row elements
When modifying a lead compound what regions are targeted for modifications?
Auxophoric Regions
What type of functional group is this?
Sulfide
What type of molecular represenation is this?
Bone line structure
What type of molecular represenation is this ?
Partically Condensed Structure (Where the C-H bonds aren’t all drawn out)
What functional group is this ?
Amine
Fischer projections are only used for what type of compounds?
Acylic
Functional Group
A characteristic group of atoms / bonds that posses a predictable chemical behavior
What type of functional group is this ?
Alkene
What type of functional group is this?
Anhydride
Lead modification
Is a techique used in forming a new drug, which involves modifying the structure of a compound known to exhibit desirable medicinal properties
What are the rules for assessing which resonance structure is important?
- Minimize the charge ( No wihout any ccharges)
- Electronegative atoms like: N, O, Cl can have a positive charge when it has an octect
- Avoid drawing a resonance structure with carbons that have opposite charges
