MODULE 5 Flashcards
Arrange the following: From most to least
dipole characteristics
I. Debye forces
II. London forces
III. Keesom forces
A. II, I, III
B. III, I, II
C. I, II, III
D. III, II, I
III, I, II
Which of the following terms is used to describe the solubility of a substance if 800 mg of the solute can be dissolved in 95 mL water
A. Slightly soluble
B. Soluble
C. Sparingly soluble
D. Practically insoluble
Slightly soluble
Lacrimal fluid has an isotonicity values
corresponding to that of NaCl solution with
the strength of
A. 0.1%
B. 9.0%
C. 1.0%
D. 0.9%
0.9%
The buffer equation is also known as
A. Noyes-whitney equation
B. Arrhenius
C. Henderson-Hasselbalch
D. Van’t hoff
Henderson-Hasselbalch
Convert 37.5 degrees Celsius to Fahrenheit
A. 98.6 degrees Fahrenheit
B. 99.5 degrees Fahrenheit
C. 100.4 degrees Fahrenheit
D. 100.3 degrees Fahrenheit
99.5 degrees Fahrenheit
Crystal symmetry of Urea
A. Cubic
B. Tetragonal
C. Hexagonal
D. Rhombic
Tetragonal
Compute for the E-value of Zinc Chloride
(MW = 135.9) with an Liso of 5.1.
A. 0.46
B. 0.64
C. 453
D. 1.22
0.64
Determine the heat required to increase the internal energy and to perform work.
A. Specific heat
B. Heat potential
C. Entropy
D. Enthalpy
Enthalpy
Which of the following is a colligative property?
A. Osmotic pressure
B. Boiling point
C. Freezing point
D. Vapor pressure
Osmotic pressure
Which of the following statements about the rate of dissolution of a solid API into an aqueous biological environment is true?
A. Increasing the particle size decreases the dissolution rate resulting in a quicker onset of action
B. Increasing the particle size increases the dissolution rate resulting in a quicker onset of action
C. Increasing the particle size increases the dissolution rate resulting in a slower onset of action
D. Increasing the particle size decreases the dissolution rate resulting in a slower onset of action
Increasing the particle size decreases the dissolution rate resulting in a quicker onset of action
Official method of the USP for determining specific gravity
A. Floatation method
B. Baume method
C. Westphal balance
D. Pycnometer method
Pycnometer method
Mesh number
A. Number of square openings per linear inch
B. Number of square inches per linear opening
C. Number of linear openings per square inch
D. Number of linear inches per square openings
Number of square openings per
linear inch
Contact angle exhibited by complete nonwetting
A. 0 degree
B. 90 degrees
C. 180 degrees
D. 360 degrees
180 degrees
Isometric (isochoric)
A. Constant heat
B. Constant temperature
C. Constant volume
D. Constant pressure
Constant volume
n optical microscopy, this is the longest tangent line that can be measured in a particle
A. Martin diameter
B. Feret diameter
C. Projected area diameter
D. Longest diameter
Feret diameter
An autonomic particle counter that uses electric resistance to determine the size of the particle
A. HIAC Royco
B. Coulter counter
C. Gelman
D. Abbe
Coulter counter
Range of HLB value in the Griffin scale for anti-foaming agents
A. 1-3
B. 3-8
C. 8-16
D. 16-18
1-3
Flow system that shows a yield value
A. Plastic
B. Pseudoplastic
C. Dilatant
D. Newtonian
Plastic
Select the INCORRECT statement about Surfactants.
A. Wetting agents aid in attaining intimate contact between solid particles and liquids.
B. Detergents reduce the surface tension and aid in wetting the surface and the dirt.
C. Surface-active agents with HLB values 3-6 are greatly lipophilic and produce water-in-oil emulsion.
D. The usual range of HLB values for surfactants used as solubilizing agents is between 1-3.
The usual range of HLB values for surfactants used as solubilizing agents is between 1-3.
The gram-molecular volume of gas at STP is equal to:
A. 1.0 L
B. 2.24 L
C. 22.4 L
D. 22.4 mL
22.4 L
Section of Quality Control Division
A. Microbiological section
B. Plant Inspection section
C. Specification & Assay
D. AOTA
AOTA
Consists of the products which have been bottled, stripped, packed, but not yet labeled
A. In-process section
B. Dispensing pharmacist
C. Inventory control
D. Production control
In-process section
Responsibility of an organization to determine the systems, facilities, & written procedures:
A. Technological element
B. Aesthetic element
C. Quality Control
D. Quality Assurance
Quality Assurance
Variations between suppliers of the same substance for:
A. Materials
B. Machines
C. Methods
D. Man
Materials
Aging & Improper care is one cause of variation of:
A. Materials
B. Machines
C. Methods
D. Man
Man
Non-compliance to cGMP can result in the following:
A. Quality variation
B. Contamination
C. Mix-ups and errors
D. AOTA
AOTA
Kills all living organism including spores & viruses:
A. Steam under pressure
B. Bacterial filtration
C. Chemical sterilization
D. NOTA
Steam under pressure
The Inspection & Checking section of QC is responsible for:
A. Sampling of raw materials
B. Chemical Assaying
C. Testing sterility of products
D. Doing pyrogen test
Sampling of raw materials
Quarantined materials delivered in the warehouse are:
A. Subject to test & assay
B. Rejected
C. Releasable to production department
D. In-process products
Subject to test & assay
Aggregates of powders which adhere or bond to each other to form larger particles:
A. Powders
B. Microcapsules
C. Pellets
D. Granules
Granules
Caused by poor mixing of the granulation:
A. Weight variation
B. Double impression
C. Sticking
D. Chipping
Weight variation
The ff. excipients impart satisfactory compression characteristics to the tablet formulation except:
A. Glidant
B. Disintegrant
C. Lubricant
D. Anti-adherents
Disintegrant
Which of the ff. additives in parenterals reduce the pain of injection in areas with nerve endings?
A. Buffers
B. Tonicity adjusters
C. Chelating agents
D. NOTA
Tonicity adjusters
Weight variation test is carried out in:
A. 10 tabs
B. 20 tabs
C. 30 tabs
D. 40 tabs
20 tabs
Method of tablet manufacture for easily compressible or adhesive ingredients is:
A. Direct compression
B. Dry method
C. Wet method
D. Slugging
Direct compression
A type of tablet coating which is a modified form of film coating differing only in the size of the particles to be coated and the method used:
A. Compression coating
B. Enteric coating
C. Marumerization
D. Microencapsulation
Microencapsulation
Improperly sealed ampoules should be
tested for:
A. Particulate matter
B. Pyrogen
C. Bacteria
D. Leak
Leak
The most inert grade of stainless steel used
for high grade products:
A. SS 304
B. SS 316
C. SS 3004
D. SS 3016
SS 316
The method for the preparation of compressed tablet wherein the granulation is formed by compacting large masses of the mixture & subsequently crushing and sizing these pieces into smaller granules
A. Dry granulation
B. Wet granulation
C. Direct compression
D. AOTA
Dry granulation
Poorly manufactured tablets with extended on the edge or periphery, this defect is called:
A. Mottling
B. Picking
C. Capping
D. Whiskering
Whiskering
Which of the following package types is tamper evident by design?
A. Plastic bottles
B. Aerosol container
C.Ointment jars
D.Sealed boxes/cartons
Aerosol container
Which of the following regulation is responsible for classifying drugs into two-OTC medicines and prescription drugs?
A. Durham-Humphrey Amendment of 1952
B. The Federal Food, Drug, And Cosmetic Act of 1938
C. Comprehensive Drug Abuse Prevention and Control Act of 1970
D.None of the above
Durham-Humphrey Amendment
of 1952
Which type of segregation occurs when the finer, lighter particles remain suspended in air longer and do not settle as quickly as the larger or denser particles?
A.Segregation
B.Fluidization
C.Sifting
D.Dusting
Dusting
Which of the following method of particle size determination is done by measuring terminal settling velocity of particles through a liquid medium and is computed by Stoke’s Law?
A. Microscopy
B. Sedimentation rate
C. Laser holography
D. Cascade Impaction
E. Light Scattering
Sedimentation rate
Which of the following distinctive looking capsules has both ends tapered?
A. Snap fit
B. Coni-snap
C. Spansules
D. Pulvules
E. Kapseals
Spansules
What is the smallest capsule size?
A.5
B. 3
C.1
D.0
E. 000
5
Which of the following ingredients is used in the preparation of sugar-free chewable tablets?
A. Xylitol
B. Lactose
C. Mannitol
D. Dextrose
E. Sucrose
Xylitol
Which of the following film coating problems refers to flaking of larger amounts of film fragments from the tablet surface?
A. Picking
B. Peeling
C. Orange Peel Effect
D. Mottling
E. Bridging
Peeling
Aquaphor is an example of what type of ointment base?
A. Hydrocarbon base
B. Absorption base
C. Water soluble base
D.Water removable base
Absorption base
What is the concentration of water in glycerogelatins?
A. 15%
B. 40%
C. 35%
D. 10%
35%
Which of the following is added to the base of the suppository to prolong drug release?
A. Citric acid
B. Beeswax
C. Alginic acid
D. Yellow wax
Alginic acid
Which of the following refers to eutectic mixtures of mono-, di-, and triglycerides derived from natural vegetable oils, each type having slightly different properties?
A. Fattibase
B. Suppocire OSI
C. Wecobee W
D. Witepsol H15
Suppocire OSI
What is the relative term of solubility of a compound if 1 gram is dissolved in 150 ml solvent?
A. Soluble
B. Sparingly soluble
C. Slightly soluble
D. Insoluble
E. Very soluble
Slightly soluble
Which mixing category is frequently encountered when highly viscous fluids are being processed?
A. Bulk transport
B. Turbulent mixing
C. Laminar mixing
D. Molecular diffusion
Laminar mixing
What is the activity of an emulsifying agent
with an HLB value of 8-18?
A. Antifoaming
B. Wetting agent
C. Emulsifier
D.Detergents
E. Solubilizers
Emulsifier
Which of the following methods of size reduction is also known as jet milling or micronizing?
A. Dry milling
B. Micropulverization
C. Fluid energy grinding
D. Spray drying
Fluid energy grinding
Which of the following is used for patients who have suffered a heavy loss of fluid and electrolyte?
A. Irrigating solution
B. Replacement therapy
C. Maintenance therapy
D. Enteral nutrition
Replacement therapy
What inert gas is used in the airspace
during packaging of injectable products?
A. Oxygen
B. Nitrogen
C. Helium
D. Carbon dioxide
Nitrogen
Formaldehyde is an example of what type of ingredient in biological products?
A. Stabilizer
B. Residual inactivating ingredient
C. Residual cell culture
D.Adjuvant
Residual inactivating
ingredient
What animal is used to prepare heterologous sera?
A. Snake
B. Mice
C. Pig
D. Monkey
E. Horse
Horse
What is the active ingredient in vitrasert implant?
A. Histrelin
B. Ganciclovir
C. Goserelin
D. Leuprodile
Ganciclovir
Which of the following is indicated for initiation and/or continuation of cervical ripening in patients at or near term when there is medical or obstetrical indication for labor induction?
A. Progestasert system
B. Dinoprostone vaginal insert
C. Estring
D. Crinone gel
Dinoprostone vaginal insert
Which of the following consist of a flexible impermeable diaphragm surrounded by a sealed layer containing an osmotic agent that is enclosed within a semipermeable membrane?
A. Films
B. Mucoadhesive system
C. Osmotic pump
D. Medicated gums
Osmotic pump
Initial application for certificate of medical device registration for class B will have a validity of how many years?
A.1 year
B.3 years
C.5 years
D.10 years
5 years
Which of the following is NOT included in the documentary requirements for application of notification and registration?
A. Notarized application form
B. Copy of letter of Authorization
C. A government-issued certificate attesting to the status of the manufacturer with regard to the competence and reliability of the personnel and facilities.
D. None of the above
None of the above
All the following are cosmetic products, EXCEPT:
A. Chemical Peeling Products
B. Make-Up Powders
C. Skin Wash Products
D. Hair Dyes
E. None of the above
Chemical Peeling Products
Cosmeceutical refers to cosmetic products that have medicinal or drug-like benefits.
Cosmeceutical is a legal term recognized by the FDA.
A.Only statement 1 is correct
B.Only statement 2 is correct
C.Both statements are correct
D.Neither of the statement is correct
Only statement 1 is correct
All the following are examples of chemical sunscreens, EXCEPT:
A. Avobenzone
B. Homosalate
C. Zinc Oxide
D. Oxybenzone
Zinc Oxide
A type of hair dye which adheres to the outside of hair fibers and partially penetrate the cuticle layers, making the hair dye longer lasting.
A.Temporary
B.Demi-permanent
C.Semi-permanent
D.Permanent
Semi-permanent
What is referred to as fairy dust and is added to a formula at a low level for the primary purpose of getting to put the ingredient name on the label?
A.Functional ingredients
B.Aesthetic modifiers
C.Claim ingredients
D.Drug actives
Claim ingredients
CIR stands for:
A.Cosmetic Ingredient Repository
B.Cosmetic Ingredient Review
C. Cosmetic Ingredient Regulation
D.Cosmetic Ingredient Rules
Cosmetic Ingredient Review
Which of the following is referred to as the
negative list?
A. ACD Annex VI
B. ACD Annex VII
C. ACD Annex II
D. ACD Annex IV
ACD Annex II
This is part of the ASEAN Cosmetic Directive Technical Documents, EXCEPT:
A. ASEAN Microbial Limit
B. ASEAN Heavy Metal Limit
C. ASEAN Botanical Safety Assessment Guidance Document
D. ASEAN Guidelines on GMP for Traditional Medicines / Health Supplements
ASEAN Guidelines on GMP for
Traditional Medicines / Health
Supplements
Cannabis sativa is considered a banned ingredient in cosmetic products based on RA 9165.
Cell, tissues, or products of human origin are allowed to be a part of cosmetic products in the Philippines.
A. Only statement 1 is correct
B. Only statement 2 is correct
C. Both statements are correct
D. Neither of the statement is correct
Only statement 1 is correct
Which of the following is found on the label of products that has been observed to have serious adverse events and potential safety hazards?
A.Precaution
B.Contraindication
C.Warning
D.Hazard
Warning
Which of the following refers to an audit that may be triggered by consumer complaints or results found on samples found in the market?
A.Internal Audit
B.Ad-hoc Audit
C.Routine Audit
D.None of the above
Ad-hoc Audit
Which of the following test is required only for raw materials of botanical origin?
A. Physical specifications
B. Mutagenicity
C. Pesticide level
D. Absence of Annex II ingredients beyond unavoidable traces
E. None of the above
Pesticide level
Done to ensure that the product is notified and compliant to current labelling requirements and guidelines.
A.Post-evaluation
B.Product verification
C.Advertisement monitoring
D.Consumer/product complaint
Product verification
The following are activities under PMS, EXCEPT:
A.Product Verification
B.Issuance of FDA Advisory
C.Post-evaluation
D.Notification Application
E.None of the above
Notification Application
“The Philippine Pharmacy Act” was
approved and signed into Law by President
Benigno Aquino III on:
A. July 23, 2016
B. May 23, 2016
C. July 21, 2016
D. May 21, 2016
July 21, 2016
This order gives comprehensive guidelines on the registration of Pharmaceutical Products to be consistent with RA 6675
A. AO 220
B. AO 42
C. AO 67
D. AO 90
E. AO 56
AO 67
It is a drug which contains no amount of, or a different active ingredient or less than 80% of the active ingredient it purports to possess, as distinguished from an adulterated drug including reduction or less of efficacy due to expiration:
A. Counterfeit drug
B. New drug
C. Investigational drug
D. Tried and tested drug
E. Ethical drugs
Counterfeit drug
Revised rules and regulations to implement Dispensing Requirements under the Generics Act of 1988:
A. AO 63
B. AO 62
C. AO 42
D. AO 55
E. AO 56
AO 63
The Universally Accessible Cheaper and
Quality Medicines Act of 2008 is known as
RA:
A. RA 9257
B. RA 9502
C. RA 9165
D. RA 9205
E. RA 9527
RA 9502
RA 9502 is an act providing for cheaper and
quality medicines, amending the Intellectual
Property Code also known as:
A. RA 8205
B. RA 8293
C. RA 8203
D. RA 8295
RA 8293
RA 9994, The Expanded Senior Citizens
Act of 2010 was signed and enacted into
law by President Gloria Macapagal Arroyo
on:
A. February 10, 2010
B. July 27, 2009
C. February 15, 2010
D. July 15, 2009
February 15, 2010
Grounds for suspension of LTO of Drug
Establishment:
A. Lapses for record keeping of
invoices
B. Sale of antibiotics without batch
certification
C. Selling of misbranded drugs
D. Serious repeated or rampant
violation of existing laws
E. Lapses in record keeping of CPR
Lapses for record keeping of
invoices
Absence of Pharmacist in a drugstore on
three inspections by BFAD inspector is a
ground:
A. Cancellation of the prof license of
the said pharmacist
B. Suspension of the LTO
C. Revocation of the LTO
D. Permanent Closure
E. Temporary Closure
Temporary Closure
It means a system of words or other
systems arbitrary used to represent words:
A. Code
B. Secret keys
C. Secret clues
D. Cipher
E. Coding
Code
The Code of Ethics for the Pharmaceutical
Profession was promulgated by the Board
of Pharmaceutical Examiners on:
A. February 28, 1924
B. February 8, 1924
C. February 18, 1924
D. NOTA
February 28, 1924
The book kept for the purpose of recording
the sale of violent poisons should be
preserved for a period of:
A. 1 year
B. 2 years
C. 4 years
D. 5 years
E. 3 years
5 years
The amount of shabu subjected to life
imprisonment to death and fine ranging from
500,000 pesos to 10M pesos.
A. 500 g
B. 10 g
C. 50 g
D. 40 g
E. 20 g
50 g
Duration of the conduct of examination in
determining the genuineness and
authenticity of the product by Bureau
A. 10 working days
B. 20 working days
C. 16 working days
D. Within 24 hours
20 working days
A drug product prescribed which is not
registered with BFAD is considered a type
of
A. Impossible Rx
B. Violative Rx
C. Erroneous Rx
D. Coded Rx
E. Registered Rx
Impossible Rx
