MODULE 1 Flashcards
Which of the following scientists created the framework that became the modern periodic table?
A. Antoine Laurent Lavoisier
B. Dmitri Mendeleev®
C. Gilbert Lewis
D. J.J. Thomson
Dmitri Mendeleev
Which of the following scientists is the father of chemistry
a. Dmitri Mendeleev
b. John Dalton
c. Antoine Laurent Lavoiser
d. Ernest Rutherford
Antoine Laurent Lavoiser
Which law states that when two elements combine with each other to form more than one compound,the weights of one element that combine with a fixed weight of the other are in ratio of small whole numbers?
a. Law of Multiple Proportions
b. Periodic Law
c. Law of Definite Proportions
d. Avogadro’s Law
Law of multiple proportions
Which of the following scientists discovered protons?
a. James Chadwick
b. Ernest Rutherford
c. Linus Pauling
d. Joseph Proust
Ernest Rutherford
Which law states samples of a compound will always contain the same proportion of elements by mass
a. Law of Multiple Proportions
b. Periodic Law
c. Law of Definite Proportions
d. Avogadro’s La
Law of Definite Proportions
The chemical formula of perchlorate ion
a. ClO-
b. C1O3-
c. CIO4-
d. ClO2-
ClO4
Which of the following is the biggest element?
a. Calcium
b. Bromine
c. Potassium
d. Arsenic
Potassium
Which of the following elements has the highest electronegativity?
a. Chlorine
b. lodine
c. Fluorine
d. Astatine
Fluorine
Which of the following is a Ketone?
a. RCOOR
b. ROR
c. RCOR
d. ROH
RCOR
Which of the following is an Arrhenius base?
a. CO2-2
b. HCI
c. CH3C00-
d. Mg(OH2)
Mg (OH2)
Which theories states that any species that can donate a proton, H+ is an acid?
a. Bronsted-Lowry Theory
b. Lewis Theory
c. Arrhenius Theory
d. Electron Donor Theory
Bronsted-Lowry Theory
Copper leads to which of the following toxicity?
a. Osteomalacia
b. Parakeratosis
c. Argyria
d. Wilson’s Disease
Wilson’s Disease
Cadmium leads to which of the following toxicity?
a. Baritosis
b. Itai-itai Poisoning
c. Wilson’s Disease
d. Parakeratosis
Itai-itai Poisoning
Which of the following is the antidote for copper poisoning?
a. Saline solution
b. Penicillamine
c. BAL
d. Magnesium sulfate
Penicillamine
Which of the following is the antidote for Iron toxicity?
a. Penicillamine
b. Copper sulfate
c. Deferoxamine
d. Saline solution
Deferoxamine
What is the chemical name for Epsom Salt?
a. Sodium chloride
b. Potassium fluoride
c. Calcium carbonate
d. Magnesium sulfate
Magnesium sulfate
Which of the following is the most abundant extracellular anion?
a. Chloride Ion
b. Potassium Ion
c. Sodium Io
d. Magnesium Ion
Chloride Ion
Which of the following is the second most abundant intracellular cation?
a. Calcium ion
b. Magnesium ion
c. Sodium ion
d. Potassium ion
Magnesium ion
What is the chemical name of Green Vitriol?
a. Ferrous Sulfate Heptahydrate
b. Zinc Sulfate Heptahydrate
c. Magnesium Sulfate Heptahydrate
d. Copper Sulfate Pentahydrate
Ferrous Sulfate Heptahydrate
What is the Chemical formula of White Vitriol
a. CuSO4.5H2O
b. MgSO4.7H2O
c. ZnSO4.7H2O
d. FeSO4.7H2O
ZnSO4.7H2O
What is the color of Helium tank/containers?
a. Green
b. Brown
c. Red
d. Yellow
Brown
What metal is present in Insulin?
a. Magnesium
b. Manganese
c. Zinc
d. Nickel
Zinc
What is the chemical name of White lotion?
a. Hydrogen sulfide
b. Magnesium stearate
c. Cadmium sulfide
d. Zinc Sulfide
Zinc Sulfide
What is the metal present in cofactor of enzymes flavin dependent enzymes?
a. Iodine
b. Fluorine
c. Molybdenum
d. Zinc
Molybdenum
What can cause lobster appearance?
a. Boric Acid
b. Cadmium Sulfide
c. Hydrated Zinc Silicate
d. Potassium nitrate
Boric Acid
What is the common name of calcium sulfate?
a. Epsom salt
b. Lover’s ink
c. Plaster of Paris
d. Green vitriol
Plaster of Paris
What is the percentage of hydrogen peroxide as antiseptic?
a. 12%
b. 3%
c. 6%
d. 9%
3%
Which of the following is a urinary acidifier?
a. Sodium carbonate
c. Ammonium Chloride
b. Sodium acetate
d. Potassium bicarbonate
Ammonium Chloride
What is the concentration of iodine in Povidone Iodine?
a. 10%
b. 5%
c. 3%
d. 2%
3%
Which of the following is used as a suspending agent in calamine lotion?
a. Kaolin
b. Bentonite
c. Pumice
d. Zinc Sulfate
Bentonite
Which of the following elements produces a Crimson red flame during a flame test?
a. Calcium
b. Lithium
c. Barium
d. Strontium
Strontium
Which of the following elements produces a green flame during a flame test?
a. Barium
b. Calcium
c. Sodium
d. Arsenic
Barium
Which of the following group of cations does not have a common precipitating agent?
a. Chloride Insoluble group
b. Base insoluble group
c. Soluble group
d. Acid insoluble group
Soluble group
Which of the following elements is used for its depressant action?
a. Calcium
b. Lithium
c. Potassium
d. Sodium
Lithium
Which antiviral drug was formerly used to treat Parkinsonism?
a. Acyclovir
b. Zidovudine
c. Amantadine
d. Abacavir
Amantadine
What is the lightest of all elements?
a. Oxygen
b. Hydrogen
c. Lithium
d. Aluminum
Hydrogen
What is the antidote for Iodine toxicity?
a. Epsom salt
b. Starch
c. Saline solution
d. BAL
Starch
Which of the following block protease enzyme to stop viral replication?
a. Saquinavir
b. Amantadine
c. Acyclovir
d. Zanamivir
Saquinavir
During which phase of the cell cycle does DNA replication occur?
a. G1 Phase
b. G2 Phase
c. M Phase
d. S Phase
S Phase
What is the mechanism of action of Ifosfamide?
a. Alkylation of DNA
b. Intercalation
c. Inhibit Topoisomerase I
d. Inhibit microtubule assembly
Alkylation of DNA
Which phase of the cell cycle is inhibited by antitumor antibiotics?
a. G1 Phase
b. G2 Phase
c. M Phase
d. S Phase
S Phase
Which of the following drugs causes cardiotoxicity?
a. Bleomycin
b. Doxorubicin
c. Methotrexate
d. Ifosfamide
Doxorubicin
What is the mechanism of action of 5-fluorouracil?
a. Inhibit dihydrofolate reductase
b. Inhibit Topoisomerase I enzyme
c. Inhibit thymidylate synthase
d. Prevent microtubule assembly
Inhibit thymidylate synthase
Which phase of the cell cycle is inhibited by ifosfamide?
a. G1 Phase
b. G2 Phase
c. M Phase
d. S Phase
G1 Phase
Which of the following is a folic acid analog?
a. Ifosfamide
b. Methotrexate
c. Carmustine
d. Paclitaxel
Methotrexate
Which of the following anticancer drugs causes Hand-Foot Syndrome?
a. Methotrexate
b. 5-Fluorouracil
c. Cisplatin
d. Busulfan
5-Fluorouracil
Which of the following is true regarding chloral hydrate?
a. Chloral hydrate stimulates the CNS
b. Chloral hydrate blocks the depressant effect of ethanol
c. Chloral hydrate is synergistic with ethanol
d. Chloral promotes excretion of ethanol
Chloral hydrate is synergistic with ethanol
Which of the following causes extrapyramidal symptoms?
a. Olanzapine
b. Aripiprazole
c. Ziprasidone
d. Haloperidol
Haloperidol
Which of the following drugs share similar structure with phenobarbital?
a. Mephensin
b. Chloral hydrate
c. Chlorpromazine
d. Glutethimide
Glutethimide
Which of the following benzodiazepines has a duration of action of 3-8 hrs?
a. Temazepam
b. Diazepam
c. Alprazolam
d. Oxazepam
Oxazepam
Which drug is used as a nerve poisons and have been used in warfare and bioterrorism and as agricultural insecticides
a. Ipratropium
b. Organophosphates
c. Bethanecol
d. Benztropine
Organophosphates
Which of the following is an Indirect irreversible cholinergic agonist
a. Bethanecol
b. Ecothiopate
c. Atropine
d. Neostigmine
Ecothiopate
Which of the following is an Indirect reversible cholinergic agonist
a. Bethanecol
b. Ecothiopate
c. Atropine
d. Neostigmine
Neostigmine
Which of the following blocks muscarinic receptors
a. Succinylcholine
b. Pancuronium
c. Pilocarpine
d. Atropine
Atropine
Which of the following is the first beta blocker
a. Propranolol
b. Dichloroisoproterenol
c. Metoprolol
d. Atenolol
Dichloroisoproterenol
Which of the ff. is a selective beta blocker
a. Solatol
b. Penbutolol
c. Timolol
d. Atenolol
Atenolol
Naphthoxylactic acid is a major metabolite of which of the ff. Drugs
a. Prazosin
b. Propranolol
c. Dobutamine
d. Terbutaline
Propranolol
What is the mechanism of action of amantadine
a. Prevent uncoating
b. Inhibit DNA Polymerase
c. Reverse transcriptase inhibitor
d. Protease inhibitor
Prevent uncoating
What is the MOA of Acyclovir
a. Prevent uncoating
b. Inhibit DNA Polymerase
c. Reverse transcriptase inhibitor
d. Protease inhibitor
Inhibit DNA Polymerase
Identify the type of bond exist between the pointed area
a. Van Der Waals forces of attraction
b. Ionic bonding
c. Dipole-dipole attraction
d. Dipole-induced dipole attraction
(Absolute negative and positive)
Ionic bonding
EVALUATE the adrenergic drug
a. Drug A can be degraded by COMT
b. Drug A cannot be degraded by COMT
c. Drug A can be degraded by MAO
d. Drug has more affinity to alpha receptors
Drug A can be degraded by COMT
Identify the type of bond exist between the pointed area
a. Van Der Waals forces of attraction
b. Ionic bonding
c. Dipole-dipole attraction
d. Dipole-induced dipole attraction
(3 wavy lines)
Van Der Waals forces of attraction
Which of the ff. is the least stable against MAO
Which of the following benzodiazepines has the shortest duration of action?
with OH group
Which of the following type of alcohol has the highest CNS depressant activity
tertiary alcohol
Which of the following phenothiazines has more anticholinergic activity
Which of the following is a secondary alcohol?
How many neutrons in a barium atom?
A. 137
B. 56
C. 193
D. 81
81
What is the mass number of the following element?
A. 13
B. 27
C. 14
D. 40
27
How many protons are in sodium atom?
A. 23
B. 11
C. 12
D. 34
11
THE ARE KNOWN AS FAST ACETYLATORS
A. ASIANS & ESKIMOS
B. ASIANS & CAUCASIANS
C. ESKIMOS & CAUCASIANS
D. NONE OF THE ABOVE
ASIANS & ESKIMOS
A PROCESS THAT CAN CHEMICALLY/PHYSICALLY DESTROY MOST VEGETATIVE MICROBES OR VIRUSES BUT CANNOT KILL SPORES
A. SANITAZATION
B. DECONTAMINATION
C. ANTISEPSIS
D. DISINFECTION
E. STERILIZATION
DISINFECTION
UTILIZED IN STERILIZATION OF HEAT SENSITIVE MEDICAL EQUIPMENT AND PHARMACEUTICALS
A. ETHYLENE OXIDE
B. GLUTARALDEHYDE
C. HEXACHLOROPHENE
D. BOTH A AND B
E. BOTH B AND C
BOTH A AND B
SHOULD BE GIVEN WITH CAUTION TO PATIENT WITH GOUT
A. AMINOSALICYLIC ACID
B. RIFAMPIN
C. ISONIAZID
D. ETHAMBUTOL
E. PYRAZINAMIDE
PYRAZINAMIDE
THEORY WHICH POSTULATES THAT A RECEPTOR WILL ALWAYS BE IN A STATE OF EQUILIBRIUM BETWEEN ACTIVE AND INACTIVE STATES
A. MACROMOLECULAR PERTURBATION THEORY
B. ACTIVATION-AGGREGATION THEORY
C. RATE THEORY
D. OCCUPANCY THEORY
E. INDUCED-FIT THEORY
ACTIVATION-AGGREGATION THEORY
PROVIDES 2ND PASS METABOLISM FOR DRUGS LEAVING THE LIVER
A. LIVER
B. GI MUCOSA
C. LUNGS
D. NASAL PASSAGES
LUNGS
WHICH OF THE FOLLOWING ANTI-TB AND ANTI-LEPROSY DRUG/S CANNOT PENETRATE THE CEREBROSPINAL FLUID
A. CLOFAZIMINE
B. STREPTOMYCIN
C. DAPSONE
D. BOTH A AND B
E. BOTH B AND C
BOTH A AND B
WHAT HAPPENS WHEN ALCOHOL CHAIN LENGTH INCREASES?
A. ANTIMICROBIAL ACTIVITY INCREASES
B. ALCOHOL CAN EASILY GO THROUGH THE MICROBIAL
MEMBRANE
C. INCRAESE VAN DER WAALS INTERACTION
D. ALL OF THE GIVEN CHOICES
ALL OF THE GIVEN CHOICES
RATE AND RATIO DETERMINES THE RECEPTOR’S BIOLOGICAL RESPONSE.
A. ACTIVATION - AGGREGATION THEORY
B. MACROMOLECULAR PERTURBATION
C. INDUCED-FIT THEORY
D. OCCUPANCY THEORY
E. RATE THEORY
MACROMOLECULAR PERTURBATION
CHLORAMPHENICOL IS THE DRUG OF CHOICE FOR TYPHOID FEVER.
MUPIRUCIN IS STRICTLY FOR EXTERNAL APPLICATION ONLY
A. STATEMENT 1 IS CORRECT. STATEMENT 2 IS INCORRECT
B. STATEMENT 1 IS INCORRECT. STATEMENT 2 IS CORRECT
C. BOTH STATEMENTS ARE CORRECT
D. BOTH STATEMENT ARE INCORRECT
BOTH STATEMENT ARE CORRECT
RESPONSE CEASES WHEN THE DRUG DISSOCIATES FROM THE RECEPTOR
A. ACTIVATION - AGGREGATION THEORY
B. MACROMOLECULAR PERTURBATION
C. INDUCED-FIT THEORY
D. OCCUPANCY THEORY
E. RATE THEORY
OCCUPANCY THEORY
MDR TB IS RESISTANT TO WHICH OF THE FOLLOWING DRUGS?
A. ETHAMBUTOL & ETHIONAMIDE
B. ISONIAZID & RIFAMPIN
C. RIFAMPICIN & PYRAZINAMIDE
D. STREPTOMYCIN & AMINOSALICYLIC ACID
E. PYRAZINAMIDE & ISONIAZID
ISONIAZID & RIFAMPIN
ANTAGONIST INDUCED A NON SPECIFIC CONFORMATIONAL
CHANGE THAT FAIL TO PRODUCE A RESPONSE
A. ACTIVATION - AGGREGATION THEORY
B. MACROMOLECULAR PERTURBATION
C. INDUCED-FIT THEORY
D. OCCUPANCY THEORY
E. RATE THEORY
INDUCED-FIT THEORY
ACTIVATION IS PROPORTIONAL TO THE TOTAL NUMBER OF
ENCOUNTERS OF A DRUG WITH ITS RECEPTORS
A. ACTIVATION - AGGREGATION THEORY
B. MACROMOLECULAR PERTURBATION
C. INDUCED-FIT THEORY
D. OCCUPANCY THEORY
E. RATE THEORY
RATE THEORY
ACCOUNTS FOR THE ACTIVITY OF INVERSE AGONIST
A. ACTIVATION - AGGREGATION THEORY
B. MACROMOLECULAR PERTURBATION
C. INDUCED-FIT THEORY
D. OCCUPANCY THEORY
E. RATE THEORY
ACTIVATION - AGGREGATION THEORY
THE FOLLOWING ARE ENZYMES THAT CATALYZE PHASE 1 REACTIONS, EXCEPT
A. AMIDASE
B. ESTERASE
C. ACETYLASE
D. DEAMINASE
E. ALCOHOL DEHYDROGENASE
ACETYLASE
AN ANTI INFECTIVE THAT ACT BOTH AS KERATOLYTIC AND KERATOGENIC
A. BENZOYL PEROXIDE
B. THYMOL
C. CRESOL
D. CHLORHEXIDINE GLUCONATE
BENZOYL PEROXIDE
GREY BABY SYNDROME IS A WELL KNOWN SIDE EFFECT OF THIS DRUG
A. MUPIROCIN
B. CLINDAMYCIN HCL
C. BACITRACIN
D. CHLORAMPHENICOL
E. VANCOMYCIN HCL
CHLORAMPHENICOL
WHICH OF THE FOLLOWING HAS A GOOD RESISTANCE
A. PIPERACILLIN
B. BENZYLPENICILLIN
C. METHICILLIN
D. AMOXICILLIN
E. TICARCILLIN
AMOXICILLIN
PRODUCT OF THE SUBMERGED FERMENTATION OF PSEUDOMONAS FLUORESCENS
A. MUPIROCIN
B. CLINDAMYCIN HCL
C. BACITRACIN
D. CHLORAMPHENICOL
E. VANCOMYCIN HCL
MUPIROCIN
THESE ARE COMMON PROBLEMS ENCOUNTERED WHEN TAKING POLYPEPTIDES, EXCEPT
A. RENAL TOXICITY
B. LACK OF SYSTEMIC ACTIVITY AFTER IV ADMINISTRATION
C. HEPATOTOXICITY
D. BOTH A & B
E. BOTH B & C
BOTH B & C
LORACARBEF
A. 1ST GENERATION
B. 2ND GENERATION
C. 3RD GENERATION
D. 4TH GENERATION
E. 5TH GENERATION
2ND GEN
CEFAZOLIN
A. 1ST GENERATION
B. 2ND GENERATION
C. 3RD GENERATION
D. 4TH GENERATION
E. 5TH GENERATION
1ST GENERATION
HAS LESSER SIDE EFFECTS COMPARED TO STREPTOMYCIN
A. NEOMYCIN SULFATE
B. KANAMYCIN SULFATE
C. TOBRAMYCIN
D. AMIKACIN
NEOMYCIN SULFATE
LESS OTOTOXIC THEN GENTAMICIN
A. KANAMYCIN
B. AMIKACIN
C. TOBRAMYCIN
D. STREPTOMYCIN
AMIKACIN
CEFUROXIME
A. 1ST GENERATION
B. 2ND GENERATION
C. 3RD GENERATION
D. 4TH GENERATION
E. 5TH GENERATION
2ND GENERATION
CEFTIBUTEN
A. 1ST GENERATION
B. 2ND GENERATION
C. 3RD GENERATION
D. 4TH GENERATION
E. 5TH GENERATION
3RD GENERATION
CEFTRIAXONE
A. 1ST GENERATION
B. 2ND GENERATION
C. 3RD GENERATION
D. 4TH GENERATION
E. 5TH GENERATION
3RD GENERATION
SOLUTION OF CLINDAMYCIN THAT CAN LAST UNTIL 32 DAYS WHEN REFRIGERATED
A. CLINDAMYCIN PHOSPHATE
B. CLINDAMYCIN PALMITATE HCL
C. CLINDAMYCIN HCL
D. BOTH A & B
E. BOTH B & C
CLINDAMYCIN PHOSPHATE
SALT FORM OF THIS DRUG PROLONGS TS DURATION OF ACTION
A. PHENOXYMETHYLPENICILLIN
B. MEZLOCILLIN SODIUM
C. BENZYPENICILLIN
D. CARBENICILLIN UNDANYL SODIUM
BENZYPENICILLIN